Results 161 to 170 of about 321,856 (269)

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Viral Pathogens Threatening Cage‐Cultured Nile Tilapia in Lake Victoria: Epidemiology, Emerging Risks and Integrated Health Management Strategies

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT The rapid expansion of cage culture for Nile tilapia (Oreochromis niloticus) in Lake Victoria is central to food security and profitable development in East Africa. Nevertheless, viral conditions affect the sustainability of this sector, with significant imbalances in livelihood, trade and aquaculture adaptability.
Richard S. Komba, Chacha J. Mwita
wiley   +1 more source

A reinforcement learning-based approach for dynamic privacy protection in genomic data sharing beacons. [PDF]

open access: yesGenome Biol
Poorghaffar Aghdam M   +5 more
europepmc   +1 more source

Democratisation By Default? Change and Continuity of Poland's Contemporary Democracy Promotion in Its Eastern Neighbourhood

open access: yesContemporary European Politics, Volume 4, Issue 2, June 2026.
ABSTRACT Following a breakdown in the post‐1989 liberal consensus that governed Polish democracy promotion in its eastern neighbours under Law and Justice's term from 2015, we can expect policy changes to Polish democracy promotion. Paying tribute to historical explanations of Poland's democracy promotion, this article links the historical legacies of ...
Wicke van den Broek
wiley   +1 more source

Retention of the Full Visual Opsin Repertoire in Some Australian Cryptozoic Lizards

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
This study investigates the link between visual evolution and fossorial habits in the endemic Australian skink genus Lerista. We provide evidence for positive site‐specific selection in all 4 cone opsins, as well as relaxed selection specific to LWS. We also provide evidence of selection linked to limb reduction, an indicator of fossorial adaptation ...
Matthew J. R. Ford   +5 more
wiley   +1 more source

Light‐Activated Nucleic Acid Amplification Systems Using Photo‐Caged DNA Polymerase or Primers

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
ABSTRACT Precise control over nucleic acid amplification is essential for achieving reliable, quantitative, high‐throughput, and multiplexed molecular diagnostics, particularly in point‐of‐care and field settings. However, conventional isothermal amplification methods, especially rapid assays at ambient temperature such as recombinase‐aided ...
Yang Wu   +20 more
wiley   +1 more source

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