Results 71 to 80 of about 393,359 (294)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Parametric matrix models

open access: yesNature Communications
We present a general class of machine learning algorithms called parametric matrix models. In contrast with most existing machine learning models that imitate the biology of neurons, parametric matrix models use matrix equations that emulate physical ...
Patrick Cook   +4 more
doaj   +1 more source

Buckling analysis of thin-walled functionally graded sandwich box beams [PDF]

open access: yes, 2015
Buckling analysis of thin-walled functionally graded (FG) sandwich box beams is investigated. Material properties of the beam are assumed to be graded through the wall thickness.
Lee, Jaehong   +7 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Influence of neutron-capture reactions on the nucleosynthesis of strontium

open access: yesCommunications Physics
The astrophysical intermediate neutron-capture process (i process) has been reinvoked in recent years to describe stellar observations that cannot be explained by the traditional nucleosynthesis processes.
Caley M. Harris   +22 more
doaj   +1 more source

Analytical solution for vibration and buckling of functionally graded sandwich beams using various quasi-3D theories [PDF]

open access: yes, 2015
This paper presents an analytical solution for vibration and buckling of functionally graded (FG) sandwich beams using various quasi-3D theories, which consider effects of both shear and normal deformation.
Lee, Jaehong   +3 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Axial-flexural coupled vibration and buckling of composite beams using sinusoidal shear deformation theory [PDF]

open access: yes, 2013
A finite element model based on sinusoidal shear deformation theory is developed to study vibration and buckling analysis of composite beams with arbitrary lay-ups.
Thai, Huu-Tai, Inam, Fawad, Vo, Thuc
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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