Results 51 to 60 of about 2,323,606 (296)
Artificial Intelligence Computing at the Quantum Level
Data, 2022 The extraordinary advance in quantum computation leads us to believe that, in the not-too-distant future, quantum systems will surpass classical systems. Moreover, the field’s rapid growth has resulted in the development of many critical tools, including
Olawale Ayoade +2 more
doaj +1 more source
Your Sewing Machine - Its Care and Adjustment [PDF]
, 1946 PDF pages ...
Barden, R. D., Bear, N. R.
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Perspectives of Key Stakeholders on the Reintroduction of Apex Predators to the United Kingdom
EcologiesApex predators were extirpated from the UK hundreds of years ago. Practitioners have recently advocated for reintroductions of predators in the UK given their role as keystone species.
Shannon Wilson, Marco Campera
doaj +1 more source
L’ours au Paléolithique. Des études orientées ?
Archéopages, 2010 Archaeological deposits containing the remains of bears are frequent in Europe. Most of them are in caves where the animals hibernated however sites specific to brown bears, which are less common, are not always in caves.
Dominique Armand
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Bovine and human becomings in histories of dairy technologies: robotic milking systems and remaking animal and human subjectivity [PDF]
, 2017 This paper positions the recent emergence of robotic or automatic milking systems (AMS) in relation to discourses surrounding the longer history of milking technologies in the UK and elsewhere.
BEAR, CHRISTOPHER, HOLLOWAY, LEWIS
core +2 more sources