Results 51 to 60 of about 573,045 (266)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
People and NatureWhile large carnivore expansion is a conservation success, it increasingly challenges pastoralism. Beyond economic value, pastoralism provides critical biodiversity and sociocultural benefits, recognized by the UN and the EU's ‘High Nature Value farming’
Valeria Salvatori +3 more
doaj +1 more source
, 1948 Black and white photograph of the exterior of the Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business.
Big Bear
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
, 1930 Bud Bowman and Big Bear standing outside the Buckeye Premium Stamp Redemption Center, Big Bear Store #1, Lane Avenue, Columbus, Ohio. The Lane Avenue store, which opened in 1934, was the first Big Bear store and the first self-service supermarket in ...
Big Bear
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Cleveland avenue bear promotion
, 1954 Black and white photograph of the Big Bear exterior located at 3515 Cleveland Ave. Columbus, Ohio. Children enjoyed going to the store with their parents because a trained bear was caged near the entrance and did tricks for those who stopped to watch ...
Big Bear
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The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Damage accumulation of bovine bone under variable amplitude loads
Bone Reports, 2016 Stress fractures, a painful injury, are caused by excessive fatigue in bone. This study on damage accumulation in bone sought to determine if the Palmgren-Miner rule (PMR), a well-known linear damage accumulation hypothesis, is predictive of fatigue ...
Abbey M. Campbell +3 more
doaj +1 more source
1958 illuminated Big Bear billboard
, 1958 Illuminated Big Bear billboard from 1958. The billboard reads, " Big Bear. Always convenient parking! Columbus most modern super markets." In 1934, an innovation in food retailing was introduced in Columbus when Wayne E.
Big Bear
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