ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Evaluation of Anticancer Activity of Curcumin Analogues Bearing a Heterocyclic Nucleus [PDF]
Mohamed Jawed Ahsan
openalex +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Abstract: Rifting and Its Bearing on the Hydrocarbon System of the Margin of Angola, West Africa
Paulino Fernando Jer oacute nimo
openalex +1 more source
Depositional environment of Paleogen amber-bearing quartz-glauconite sands from Zdolbuniv (Rivne region, NW Ukraine): mineralogical and petrological evidences [PDF]
Lucyna Natkaniec‐Nowak +9 more
openalex +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Plate-tensioned reconstruction nail for proximal femur diaphyseal nonunion. [PDF]
Patterson JT +3 more
europepmc +1 more source
Evaluation of a series hybrid thrust bearing at DN values to three million. 2: Fabrication and testing [PDF]
Results of tests made to determine the experimental performance of a series hybrid bearing are reported. The bearing consists of a 150 mm ball bearing and a centrifugally actuated, conical, fluid film bearing fitting an envelope with an outer radius of ...
Eusepi, M., Winn, L. W.
core +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
The Role of Weight-Bearing Computed Tomography in the Assessment and Management of Charcot Foot Deformity: A Narrative Review. [PDF]
Kim NY, Yi Y.
europepmc +1 more source

