Results 51 to 60 of about 1,083,358 (272)
Excerpts from the Novel, Bear War-den [PDF]
, 2018 A woman park warden who works in Rocky Mountain National Park spends her time on such tasks as bear patrol, locating tourists who are lost or in other physical danger, and policing park rules.
Demuth, Vivian
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Metabolic derangements and reduced survival of bile-extracted Asiatic black bears (Ursus thibetanus)
BMC Veterinary Research, 2019 Background Across China and Southeast Asia, an estimated 17,000 bears are currently farmed for bile, primarily for traditional medicines. Depending on country, bile is extracted daily via transabdominal gallbladder fistulas, indwelling catheters, or ...
Monica Kaho Herkules Bando +11 more
doaj +1 more source
Metabolic changes in summer active and anuric hibernating free-ranging brown bears (ursus arctos) [PDF]
, 2013 The brown bear (Ursus arctos) hibernates for 5 to 6 months each winter and during this time ingests no food or water and remains anuric and inactive.
Anderstam, Björn +14 more
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Who Bears the Growing Cost of Science at Universities? [PDF]
, 2003 Scientific research has come to dominate many American university campuses. The growing importance of science is due to exciting breakthroughs in biology, information technology and advanced materials that have promise of tremendously improving human ...
Ehrenberg, Ronald G +2 more
core +2 more sources
Scattering of quantum wave packets by shallow potential islands: a quantum lens [PDF]
, 2013 We consider the problem of quantum scattering of a localized wave packet by a weak Gaussian potential in two spatial dimensions. We show that, under certain conditions, this problem bears close analogy with that of focusing (or defocusing) of light rays ...
Arseni Goussev +7 more
core +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source