Results 81 to 90 of about 1,083,358 (272)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Daylight overdrafts: who really bears the risk? [PDF]

open access: yes
Payment systems ; Federal Reserve banks ; Electronic funds transfers ...
Robert T. Clair
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Public Perceptions of Bears and Management Interventions in Japan

open access: yesHuman-Wildlife Interactions, 2017
Conservation of bears is a challenge globally. In Japan, Asiatic black bears (Ursus thibetanus) and brown bears (Ursus arctos) are considered a nuisance because of agricultural and property damage and personal human danger due to occasional human ...
Ryo Sakurai, Susan K. Jacobson
doaj   +1 more source

Venice in the East: Renaissance Crete and Cyprus [PDF]

open access: yes, 2019
This music bears witness to how ancient Greek and Latin liturgical traditions were richly embellished during the Renaissance on the islands of Crete and Cyprus, all within the shared cultural space of Venetian rule.
Lingas, A.
core  

Dr Bear and the adventure Bears [PDF]

open access: yesChildren's Geographies, 2018
“Hello, I see you have a bear on your stand. Why is that?” I ask the man behind the table which is loaded with academic journals, books and promotional literature for delegates at the RGS-IBG 2017 conference to browse through. He smiles and replies, “That’s Barnaby. He’s my bear.” He picks up the bear to give it a cuddle.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effects of Aversive Conditioning on Behavior of Nuisance Louisiana Black Bears

open access: yesHuman-Wildlife Interactions, 2017
Complaints associated with nuisance activity by Louisiana black bears (Ursus americanus luteolus) in south Louisiana have steadily increased since 2000, demanding intervention by state and federal agencies.
Jennifer Leigh, Michael J. Chamberlain
doaj   +1 more source

Retirement Savings and Household Wealth: Trends from 2001 to 2004 [PDF]

open access: yes, 2006
[From Summary] Since about 1980, the proportion of workers who participate in employer sponsored retirement plans has remained stable at about half of the workforce.
Purcell, Patrick
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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