Results 141 to 150 of about 564,247 (303)
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
POETESS ANGELA BACIU OR... ABOUT CULTURE, BEAUTY, GENEROSITY
ACROSSInterview with Romanian poetess Angela ...
Alina Beatrice CHEȘCĂ
doaj
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Journal of Architecture, Art & Humanistic ScienceWho is "beautiful" and who is "ugly"? My concept is one of the most controversial aesthetic concepts throughout history. For thousands of years, the goal of art has been to create a sense of beauty; In order to explore the nature of perception and ...
Dr/ Walaa Mohamed Zaki
doaj +1 more source
, 2022 The beauty industry has been booming in the last few years, generating immense profits as it now translates into an Internet global beauty culture in its own right that finally made room for women of color. As research barely mentions African women and their diasporas, this study aims to critically analyze the dynamic of this North American-dominated ...
openaire +1 more source
Gendered Geographies in Puerto Rican Culture: Spaces, Sexualities, Solidarities
, 2016 This is a critical study of the construction of gendered spaces through feminine labor and capital in Puerto Rican literature and film (1950-2010). It analyzes gendered geographies and forms of emotional labor, and the possibility that they generate ...
Rangelova, Radost A.
core
Advanced Science, EarlyView.CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He +17 more
wiley +1 more source
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
Advanced Science, EarlyView.With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
Challenging Hierarchies Through Animality: Interspecies and Gender Relations in Disney's <i>Beauty and the Beast</i> and <i>The Princess and the Frog</i>. [PDF]
Animals (Basel)Jacquet C.
europepmc +1 more source
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source