Results 131 to 140 of about 544,111 (303)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

THE SOCIO-PSYCHOLOGICAL PHENOMENON OF "REJECTED TATIANA" AND ASPIRATION TO AN UNATTAINABLE STANDARD OF BEAUTY IN WOMEN WHO HAVE DECIDED TO UNDERGO PLASTIC SURGERY

Siberian Journal of Life Sciences and Agriculture
The article is devoted to the study of the characteristics of women who, in pursuit of an unattainable standard of beauty, manage their appearance and body through the services of plastic surgeons. Purpose.
Svetlana D. Gurieva, Diana V. Keplat, Ekaterina A. Yumkina   +2 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

The constraints of stereotypical beauty standards on women

SHS Web of Conferences
The allure of idealized body images portrayed in social short videos serves as a poignant reflection of the media's relentless scrutiny of individual appearance and body standards, further exacerbating the pervasive anxieties surrounding personal physicality.
openaire   +2 more sources

Cultural evolution of human beauty standards

Beauty standards shape self-perception and health through social comparison and objectification, while exposure to idealized imagery exacerbates body-image concerns. Media and fashion are central arbiters of these ideals, yet long-term, quantitative, intersectional studies on how representation has changed remain scarce.
Boucherie, Louis, Kumar, Sagar, Ledebur, Katharina, Lohse, August, Sliwa, Karolina   +4 more
openaire   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

Self-Image and Beauty Standards in the Drama My ID is Gangnam Beauty

Academia Open
General Background the representation of self-image in media plays a significant role in shaping societal beauty standards. Specific Background this study focuses on the perceptions of audiences regarding self-image in the South Korean drama My ID is Gangnam Beauty, which addresses issues of beauty and self-esteem.
Dea Ramadhanty, Nur Maghfirah Aesthetika
openaire   +1 more source

Unpacking beauty norms and body image: Development and validation of the perceptions of beauty standards scale

Sage Open Medicine
Objectives: Perceptions of beauty, deeply rooted in societal norms, significantly impact self-esteem, self-concept, and mental well-being. This study aimed to develop and validate the Perceptions of Beauty Standards Scale, a tool designed to assess how individuals perceive societal beauty standards.
Shishir Paudel, Anisha Chalise, Shaina Tamrakar, Dhurba Khatri   +3 more
openaire   +3 more sources