Chasing Digital Perfection in a Filtered World: The Role of Dermatologists in Addressing Social Media Dysmorphia. [PDF]
Frasier K +3 more
europepmc +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Beyond the mirror: the impact of mainstream beauty standards on diasporic caribbean women
LAUREA MAGISTRALEQuesta tesi indaga l'impatto degli standard di bellezza sull'identità personale, l'autostima e la rappresentazione culturale nella moda e nello spettacolo, con particolare attenzione alle donne latinoamericane e caraibiche.
Perez, Alianny Melina
core
Med Spas: Patient Safety and Accreditation. [PDF]
Singer R, Jewell M, Saltz R, Fiala T.
europepmc +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Context matters: reconsidering resilience factors in dehumanization pathways to dysfunctional eating among transgender and gender diverse individuals. [PDF]
Bonato M +8 more
europepmc +1 more source
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu +10 more
wiley +1 more source
Digital culture and aesthetic orientation: associations with body perception and beauty perception on social media. [PDF]
Öztunç M +3 more
europepmc +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Confronting Beauty Standards in Scott Westerfeld's 'Uglies
This study attempts to reveal the beauty standard concept that is confronted by the main character in Scott Westerfeld’s Uglies (2005) novel. It focuses on the issue of beauty standards criteria and the way the main character confronts it.
Siti Khodifatul Fauziah
core +1 more source

