The impact of prior information on estimates of disease transmissibility using Bayesian tools [PDF]
, 2015 The basic reproductive number (R₀) and the distribution of the serial interval (SI) are often used to quantify transmission during an infectious disease outbreak.
Archer, Brett N. +3 more
core +17 more sources
Baseline fat fraction is a strong predictor of disease progression in Becker muscular dystrophy [PDF]
NMR in Biomedicine, 2022 In Becker muscular dystrophy (BMD), muscle weakness progresses relatively slowly, with a highly variable rate among patients. This complicates clinical trials, as clinically relevant changes are difficult to capture within the typical duration of a trial. Therefore, predictors for disease progression are needed.
Thom T. J. Veeger +7 more
openaire +3 more sources
Patients With Becker Muscular Dystrophy Have Severe Paraspinal Muscle Involvement
Frontiers in Neurology, 2021 Introduction: Paraspinal muscles are important for gross motor functions. Impairment of these muscles can lead to poor postural control and ambulation difficulty.
Aisha M. Sheikh +5 more
doaj +1 more source
Frontiers in Neurology, 2021 Introduction: With the advent of emerging molecular therapies for muscular dystrophies, the need for knowledge about natural history course of such diseases is of utmost importance in the preparation for future trials.
Aisha M. Sheikh +3 more
doaj +1 more source
Creation of a novel algorithm to identify patients with Becker and Duchenne muscular dystrophy within an administrative database and application of the algorithm to assess cardiovascular morbidity [PDF]
, 2019 BACKGROUND: Outcome analyses in large administrative databases are ideal for rare diseases such as Becker and Duchenne muscular dystrophy. Unfortunately, Becker and Duchenne do not yet have specific International Classification of Disease-9/-10 codes.
Burnette, W. Bryan +9 more
core +1 more source
Immunity to Soil-Transmitted Helminths: Evidence From the Field and Laboratory Models
Frontiers in Immunology, 2020 Infection with soil-transmitted helminths (STH) remains a major burden on global health and agriculture. Our understanding of the immunological mechanisms that govern whether an individual is resistant or susceptible to infection is derived primarily ...
Stefano A. P. Colombo +1 more
doaj +1 more source
Frontiers in Bioscience-Scholar, 2022 Background: Stress-inducible heat shock protein 70 (HSP70) is both a protective chaperone involved in protein homeostasis and an immune regulator. In both capacities, HSP70 has been implicated in muscle disorders, yet with fragmented and differing ...
Gwenny Cosemans +3 more
doaj +1 more source
Classification of and the latest photoelectric therapy for epidermal nevi
Chinese Journal of Plastic and Reconstructive Surgery, 2022 An epidermal nevus (EN) is a common disease of various types, including verrucous EN, nevus sebaceous, inflammatory linear verrucous EN, Becker nevus, smooth muscle hamartoma, and nevus comedonicus.
Liyun Liu, Huijing Wang, Jiying Dong
doaj +1 more source
Project MOSI: rationale and pilot-study results of an initiative to help protect zoo animals from mosquito-transmitted pathogens and contribute data on mosquito spatio–temporal distribution change [PDF]
, 2015 Mosquito-borne pathogens pose major threats to both wildlife and human health and, largely as a result of unintentional human-aided dispersal of their vector species, their cumulative threat is on the rise.
Albertini, M +16 more
core +2 more sources
Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. [PDF]
PLoS ONE, 2016 Duchenne and Becker muscular dystrophy severity depends upon the nature and location of the DMD gene lesion and generally correlates with the dystrophin open reading frame.
Zhi Yon Charles Toh +7 more
doaj +1 more source