Results 131 to 140 of about 6,773 (176)

Duchenne and Becker Muscular Dystrophies

Neurologic Clinics, 2014
The dystrophinopathies Duchenne and Becker muscular dystrophies (DMD and BMD) represent the most common inherited disorders of muscle. Improvements in cardiac care, attention to respiratory function, and judicious use of spinal correction surgery have led to increased survival in the DMD population.
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Biomarkers in Duchenne and Becker muscular dystrophies

Muscle & Nerve, 2021
See article on pages 43–49 in this issue.
Hugh J, McMillan, Hanns, Lochmüller
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Muscle histology in becker muscular dystrophy

Muscle & Nerve, 1991
AbstractTwenty patients with Becker muscular dystrophy (BMD), confirmed by dystrophin tests, were studied histologically. There were several morphological differences between younger (≤15‐year‐old) and older (>15‐year‐old) patients. In the younger patients, active muscle fiber necrosis followed by a regenerating process was conspicuous. In the older
M, Kaido, K, Arahata, E P, Hoffman, I, Nonaka, H, Sugita   +4 more
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Becker-like muscular dystrophy in sisters

European Archives of Psychiatry and Clinical Neuroscience, 1995
Two sisters with muscular dystrophy of Becker-like clinical features presented. Muscle weakness was most prominent in the pelvic girdle, but in the elder sister the distal muscles of the lower extremities were also affected. The progression was different in the siblings: The older sister showed a more pronounced deterioration than the younger.
P, Diószeghy, M, Molnár, F, Mechler
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Cardiac transplantation in becker muscular dystrophy

Journal of Neurology, 1988
A 23-year-old man with X-linked Becker type muscular dystrophy underwent cardiac transplantation because of dilated cardiomyopathy which was complicated by terminal heart failure. Impairment of muscle function was mild and slowly progressive, whereas the cardiac disease was severe and rapidly progressive.
F, Casazza, G, Brambilla, A, Salvato, L, Morandi, E, Gronda, E, Bonacina   +5 more
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Update in Duchenne and Becker muscular dystrophy

Current Opinion in Neurology, 2019
Purpose of review The purpose of this review is to highlight updates in the standard of care recommendations for DMD, and to describe approaches to and recent advances in genetic therapies for DMD. Recent findings Treatment of DMD patients with the corticosteroids prednisone or ...
Megan A, Waldrop, Kevin M, Flanigan
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Epilepsy in Duchenne and Becker muscular dystrophies

European Journal of Paediatric Neurology, 1997
Duchenne and Becker muscular dystrophies are X-linked allelic disorders in which the association of central nervous system dysfunction, typically in the form of mental retardation, is a well recognized feature. They are both due to mutations in the dystrophin gene, whose corresponding protein products are expressed both in the muscle and central ...
F, Goodwin, F, Muntoni, V, Dubowitz
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Electroretinogram in Duchenne/Becker Muscular Dystrophy

Pediatric Neurology, 1998
The authors studied all cases with dystrophinopathy consecutively reviewed between May 1995 and December 1996 by means of electroretinography (ERG), which was recorded using skin eyelid electrodes and with standard flash stimulation. This methodology can detect the functional abnormalities associated with dystrophinopathies. The most valuable parameter
S I, Pascual Pascual, J, Molano, I, Pascual-Castroviejo   +2 more
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Cardiac dysfunction with Becker muscular dystrophy

American Heart Journal, 1996
Cardiac function was examined in 21 patients with Becker muscular dystrophy (BMD) and compared with 43 patients with Duchenne muscular dystrophy (DMD) and 37 healthy control subjects. Electrocardiography showed myocardial damage was most frequently found in the lateral wall, compatible with autopsy findings.
M, Saito, H, Kawai, M, Akaike, K, Adachi, Y, Nishida, S, Saito   +5 more
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Prednisone Therapy in Becker's Muscular Dystrophy

Journal of Child Neurology, 2001
Two boys with Becker's muscular dystrophy had a dramatic and sustained improvement in strength with therapeutic use of prednisone. Both had documented Xp-21 defects on DNA testing. Concurrently with improvement, there was a decrease in their serum creatine kinase levels. One patient had two muscle biopsies, the first before prednisone treatment and the
Stanley D. Johnsen, Blue Bird Clinic
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