Results 11 to 20 of about 54,841 (223)

Acute hepatotoxicity of intravenous amiodarone in a Becker muscular dystrophy patient with decompensated heart failing and ABCB4 gene mutation: as assessed for causality using the updated RUCAM [PDF]

Journal of Cardiothoracic Surgery
Background Cardiac dysfunction, including arrhythmias, may be one of the main clinical manifestations of Becker muscular dystrophy (BMD). Amiodarone is widely used to treat arrhythmia.
Hui Shi, Ruizhen Chen, Minghui Li, Junbo Ge   +3 more
doaj   +2 more sources

Atypical reaction to anesthesia in Duchenne/Becker muscular dystrophy [PDF]

Revista Brasileira de Anestesiologia, 2018
Background and objectives Duchenne/Becker muscular dystrophy affects skeletal muscles and leads to progressive muscle weakness and risk of atypical anesthetic reactions following exposure to succinylcholine or halogenated agents.
Helga Cristina Almeida da Silva, Marcia Hiray, Mariz Vainzof, Beny Schmidt, Acary Souza Bulle Oliveira, José Luiz Gomes do Amaral   +5 more
doaj   +6 more sources

Global prevalence of Duchenne and Becker muscular dystrophy: a systematic review and meta-analysis

Journal of Orthopaedic Surgery and Research, 2022
Background A variety of mutations in the largest human gene, dystrophin, cause a spectrum from mild to severe dystrophin-associated muscular dystrophies.
N. Salari, Behnaz Fatahi, E. Valipour, Mohsen Kazeminia, Reza Fatahian, Ali Akbar Kiaei, S. Shohaimi, M. Mohammadi   +7 more
semanticscholar   +1 more source

A review of diagnosis of Duchenne and Becker muscular dystrophy [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2021
Duchenne muscular dystrophy and Becker muscular dystrophy are progressive serious neuromuscular disorders. We have reviewed contemporary data on diagnosis of DMD and BMD. Searches were carried out from 2010 to 2020. This article discusses clinical signs,
Dana Chunkayeva, Altynshash Jaxybayeva
doaj   +1 more source

Diffusion‐tensor magnetic resonance imaging captures increased skeletal muscle fibre diameters in Becker muscular dystrophy

Journal of Cachexia, Sarcopenia and Muscle, 2023
Becker muscular dystrophy (BMD) is an X‐linked disorder characterized by slow, progressive muscle damage and muscle weakness. Hallmarks include fibre‐size variation and replacement of skeletal muscle with fibrous and adipose tissues, after repeated ...
D. Cameron, Tooba Abbassi-Daloii, L. Heezen, N. M. van de Velde, Z. Koeks, T. Veeger, M. Hooijmans, Salma el Abdellaoui, S. V. van Duinen, J. Verschuuren, M. van Putten, Annemieke Aartsma-Rus, V. Raz, P. Spitali, E. Niks, H. Kan   +15 more
semanticscholar   +1 more source

Givinostat for Becker muscular dystrophy: A randomized, placebo-controlled, double-blind study

Frontiers in Neurology, 2023
Objective No treatments are approved for Becker muscular dystrophy (BMD). This study investigated the efficacy and safety of givinostat, a histone deacetylase pan-inhibitor, in adults with BMD.
G. Comi, E. Niks, K. Vandenborne, C. Cinnante, H. Kan, R. Willcocks, D. Velardo, F. Magri, M. Ripolone, Jules J. van Benthem, N. M. van de Velde, Simone Nava, L. Ambrosoli, S. Cazzaniga, P. Bettica   +14 more
semanticscholar   +1 more source

Intron mutations and early transcription termination in Duchenne and Becker muscular dystrophy

Human Mutation, 2022
DMD pathogenic variants for Duchenne and Becker muscular dystrophy are detectable with high sensitivity by standard clinical exome analyses of genomic DNA.
M. Waldrop, S. Moore, K. Mathews, B. Darbro, Livja Medne, R. Finkel, A. Connolly, T. Crawford, D. Drachman, N. Wein, Ali A. Habib, Monika Krzesniak‐Swinarska, C. Zaidman, James J. Collins, M. Jokela, B. Udd, J. Day, Gloria Ortiz-Guerrero, Jeff Statland, R. Butterfield, D. Dunn, R. Weiss, K. Flanigan   +22 more
semanticscholar   +1 more source

Patients With Becker Muscular Dystrophy Have Severe Paraspinal Muscle Involvement

Frontiers in Neurology, 2021
Introduction: Paraspinal muscles are important for gross motor functions. Impairment of these muscles can lead to poor postural control and ambulation difficulty.
Aisha M. Sheikh, Karen Rudolf, Josefine de Stricker Borch, Tahmina Khawajazada, Nanna Witting, John Vissing   +5 more
doaj   +1 more source

Muscle histological changes in a large cohort of patients affected with Becker muscular dystrophy

Acta Neuropathologica Communications, 2022
Becker muscular dystrophy (BMD) is a severe X-linked muscle disease. Age of onset, clinical variability, speed of progression and affected tissues display wide variability, making a clinical trial design for drug development very complex.
M. Ripolone, D. Velardo, S. Mondello, S. Zanotti, F. Magri, Elisa Minuti, S. Cazzaniga, F. Fortunato, P. Ciscato, Francesca Tiberio, M. Sciacco, M. Moggio, P. Bettica, G. Comi   +13 more
semanticscholar   +1 more source

Low dystrophin variability between muscles and stable expression over time in Becker muscular dystrophy using capillary Western immunoassay

Scientific Reports, 2021
Becker muscular dystrophy (BMD) is the milder allelic variant of Duchenne muscular dystrophy, with higher dystrophin levels. To anticipate on results of interventions targeting dystrophin expression it is important to know the natural variation of ...
Z. Koeks, A. Janson, C. Beekman, M. Signorelli, H. A. van Duyvenvoorde, J. C. van den Bergen, M. Hooijmans, I. Alleman, I. Hegeman, J. Verschuuren, J. C. V Deutekom, P. Spitali, N. Datson, E. Niks   +13 more
semanticscholar   +1 more source