Results 31 to 40 of about 17,304 (263)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella   +5 more
wiley   +1 more source

Sediment Bed-Load Transport: A Standardized Notation

open access: yesGeosciences, 2020
Morphodynamic processes on Earth are a result of sediment displacements by the flow of water or the action of wind. An essential part of sediment transport takes place with permanent or intermittent contact with the bed.
Ulrich Zanke, Aron Roland
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

Bed-Load Transport Equation on Arbitrarily Sloping Beds [PDF]

open access: yesJournal of Hydraulic Engineering, 2008
This work presents a simple tool to evaluate bed-load transport intensity and direction on arbitrarily sloping beds with local longitudinal and transversal inclinations up to 25° and in the case of uniform sediments and low values of the applied Shields stress.
FRANCALANCI, SIMONA, SOLARI, LUCA
openaire   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti   +6 more
wiley   +1 more source

Collisional transport model for intense bed load

open access: yesJournal of Hydrology and Hydromechanics, 2020
In an open channel with a mobile bed, intense transport of bed load is associated with high-concentrated sediment-laden flow over a plane surface of the eroded bed due to high bed shear.
Matoušek Václav, Zrostlík Štěpán
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

open access: yesAdvanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice   +2 more
wiley   +1 more source

Whit ham method of the expansion near the wave front propagating on the river with bed load transport

open access: yesVietnam Journal of Mechanics, 1990
In this paper the non linear differential equation describing the behavior of water surface behind the wave front is obtained by Whit ham method. It is shown that the bed load transport could influence significantly on the stability of the flood wave ...
Pham Hung
doaj   +1 more source

Investigation of Bed Load Transport Through Rockfill Dam [PDF]

open access: yesعلوم و مهندسی آبیاری, 2015
Due to environmental considerations, using permeable control structures in rivers have been widely welcomed by engineers working on different aspects of rivers. Impermeable structures such as rockfill dams could provide more suitable hydraulic conditions
Pouria Asiaban   +2 more
doaj   +1 more source

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