Results 121 to 130 of about 25,794 (245)

Acute GIP and GLP‐1 Administration Exerts Differential Metabolic Effects in Totally Pancreatectomised Individuals

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims While being recognised for stimulating pancreatic insulin secretion, GIP and GLP‐1 exert various extrapancreatic effects relevant in the context of incretin‐based therapies. Here, we evaluated the extrapancreatic effects of GIP and GLP‐1, separately and combined, on postprandial physiology in totally pancreatectomised individuals ...
Liva S. L. Krogh   +8 more
wiley   +1 more source

Regional and local divergence in welfare provision in England and Wales, 1776–1815

open access: yesThe Economic History Review, EarlyView.
Abstract This article uses the township‐level data on welfare expenditure and provision gathered by parish officers in England and Wales at three points between 1776 and 1815 to illuminate regional and local differences during the period. These data have been linked to geographic information system (GIS) mapping systems, facilitating the mapping of ...
John Broad
wiley   +1 more source

Predictors of parental literacy involvement: The role of interparental conflict and couple relationship quality

open access: yesFamily Relations, EarlyView.
Abstract Objective This study explores the longitudinal association between the frequency of interparental conflict and parental literacy involvement among married couples. Couple relationship quality was examined as a potential mediator in this process, while conflict resolution was included as a potential moderator in the link between interparental ...
Qiujie Gong, Karen Z. Kramer
wiley   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

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