Results 31 to 40 of about 9,251 (303)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Compost and rice hulls to increase the sustainability of substrates for bedding plant production

open access: yes, 2023
Although the search for alternatives to peat for soilless cultivation began several decades ago, no material has yet been fully substituted for it into the formulation of substrates. Similarly, perlite (PE), an amendment often used to increase air-filled
Nicoletto C.   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Methods for growth regulation of greenhouse produced ornamental pot- and bedding plants – a current review

open access: yesFolia Horticulturae, 2017
Chemical plant growth regulators (PGRs) are used in the production of ornamental potted and bedding plants. Growth control is needed for maximizing production per unit area, reducing transportation costs and to obtain a desired visual quality.
Bergstrand Karl-Johan I.
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Assessment of genetic diversity in China aster [Callistephus chinensis (L.) Nees

open access: yesJournal of Horticultural Sciences, 2023
China aster [Callistephus chinensis (L.) Nees] is a flowering annual mainly cultivated for loose flower and cut flower, bedding and pot culture. To assess the genetic diversity, 42 genotypes were evaluated for fourteen quantitative traits. The genotypes
Bhargav Veluru   +4 more
doaj   +1 more source

Low-Temperature Storage of Bedding-Plant Plugs [PDF]

open access: yesHortScience, 1992
Ageratum, begonia, marigold, and salvia seedlings in plug cells were stored in coolers to determine the effects of temperature, light, and storage time on growth and forcing time of seedlings after transplanting, and to determine the optimum storage temperatures for each crop.
Royal D. Heins   +2 more
openaire   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Experimental method for determination of the pressure distribution in granular solids

open access: yesResearch in Agricultural Engineering, 2003
This paper presents two methods of determination of pressure distribution in rape seeds. The study utilized hydraulic pressure sensors with active rubber face and stress state transducer with six duralumin face sensors.
R. Rusinek
doaj   +1 more source

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