Results 1 to 10 of about 185,151 (309)

Humdrum Tasks of the Salaried Men: Edwin Williams, a London County Council Architect at War [PDF]

open access: yesFootprint, 2015
Working at the London County Council Architects’ Department through the 1930s to 1950s, and known (if at all) as a member of the design team for the Royal Festival Hall, Edwin Williams is usually presented as a regressive figure, his design work marked ...
Nick Beech
doaj   +5 more sources

Microfluidic-Assisted ZIF-Silk-Polydopamine Nanoparticles as Promising Drug Carriers for Breast Cancer Therapy

open access: yesPharmaceutics, 2023
Metal–organic frameworks (MOFs) are heralded as potential nanoplatforms for biomedical applications. Zeolitic imidazolate framework-8 (ZIF-8), as one of the most well known MOFs, has been widely applied as a drug delivery carrier for cancer therapy ...
Zijian Gao   +6 more
doaj   +1 more source

HSV1716 Prevents Myeloma Cell Regrowth When Combined with Bortezomib In Vitro and Significantly Reduces Systemic Tumor Growth in Mouse Models

open access: yesViruses, 2023
Multiple myeloma remains largely incurable due to refractory disease; therefore, novel treatment strategies that are safe and well-tolerated are required.
Simon Tazzyman   +8 more
doaj   +1 more source

Macrophage Delivered HSV1716 Is Active against Triple Negative Breast Cancer

open access: yesFuture Pharmacology, 2022
Oncolytic viruses (OV) promote anti-tumour responses through the initiation of immunogenic cancer cell death which activates the host’s systemic anti-tumour immunity.
Amy Kwan   +15 more
doaj   +1 more source

Oncolytic Virotherapy Treatment of Breast Cancer: Barriers and Recent Advances

open access: yesViruses, 2021
Oncolytic virotherapy (OV) is an emerging class of immunotherapeutic drugs. Their mechanism of action is two-fold: direct cell lysis and unmasking of the cancer through immunogenic cell death, which allows the immune system to recognize and eradicate ...
Amy Kwan   +2 more
doaj   +1 more source

Hellenic Beech Forests Database (Hell-Beech-DB) [PDF]

open access: yesBiodiversity & Ecology, 2012
The Hellenic Beech Forests Database (GIVD ID EU-GR-007) includes releves dominated or co-dominated by Fagus sylvatica s.l. It includes almost all published releves from the northeast, north-central and east-central floristic regions of Greece. Ca. 50 unpublished releves have been already entered and more than 300 new releves are going to be entered ...
Tsiripidis, Ioannis   +4 more
openaire   +2 more sources

Researching the Teaching Context: Faithful Practice [PDF]

open access: yes, 2013
Christian teachers are called to a teaching practice that is biblically grounded or based on a biblical world and life view, but can the same imperative be applied to those wishing to conduct research in Christian education contexts? This paper considers
Beech, Geoff
core   +3 more sources

Effects of cannabis oil extract on immune response gene expression in human small airway epithelial cells (HSAEpC): implications for chronic obstructive pulmonary disease (COPD)

open access: yesJournal of Cannabis Research, 2020
Background Chronic obstructive pulmonary disease (COPD) is commonly associated with both a pro-inflammatory and a T-helper 1 (Th1) immune response.
Stephen W. Mamber   +5 more
doaj   +1 more source

Oestrogen and zoledronic acid driven changes to the bone and immune environments: Potential mechanisms underlying the differential anti-tumour effects of zoledronic acid in pre- and post-menopausal conditions

open access: yesJournal of Bone Oncology, 2020
Late stage breast cancer commonly metastasises to bone and patient survival averages 2–3 years following diagnosis of bone involvement. One of the most successful treatments for bone metastases is the bisphosphonate, zoledronic acid (ZOL).
Christopher N. George   +5 more
doaj   +1 more source

How Could Sensor-Based Measurement of Physical Activity Be Used in Cardiovascular Healthcare?

open access: yesSensors, 2023
Physical activity and cardiovascular disease (CVD) are intimately linked. Low levels of physical activity increase the risk of CVDs, including myocardial infarction and stroke.
Megan E. Hughes, Timothy J. A. Chico
doaj   +1 more source

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