Results 91 to 100 of about 4,852,263 (194)
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
MEFV Gene Mutations in Behçet’s Disease
Behçet's disease is a chronic inflammatory multisystemic disorder of unknown cause, characterized by orogenital ulcers, uveitis, skin lesions, vascular, locomotor, pulmoner, gastrointestinal, and central nervous system manifestations.
Fazile Hatipoğlu Erdem
doaj
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller +16 more
wiley +1 more source
Assessment of neurocognitive function in patients with Behçet’s disease
Introduction There is limited knowledge on cognitive performance in Behçet’s disease (BD), the majority of which come from patients with neuro-Behçet’s disease.
Rasha M. Ghaleb, Hussin M. Said
core +1 more source
Peripheral ulcerative keratitis: an unusual primary ocular manifestation in Behçet’s disease [PDF]
Behçet’s disease is an idiopathic systemic inflammation with a predilection for skin and mucosal surfaces of the eye. We report a case with Behçet’s disease associated with peripheral ulcerative keratitis and corneal perforation in the left eye.
Mogra, Shailesh; Military Hospital Ahmedabad, Ahmedabad Cantonment, Shahibaug, Ahmedabad, India +1 more
core +1 more source
Successfully treated isolated renal artery pseudoaneurysm in a patient with Behçet's disease
Renal artery aneurysms and pseudoaneurysms are an uncommon clinical problem with a low incidence rate. They are abnormal dilatations of the vessel lumen with some different natures.
Sihyung Park +5 more
doaj +1 more source
ABSTRACT Axillary artery aneurysm is an uncommon subtype of peripheral arterial aneurysm, and mural thrombus within the aneurysm sac frequently dislodges to trigger recurrent refractory acute upper extremity arterial embolism. This study reports a 57‐year‐old male patient who suffered immediate re‐embolization after isolated percutaneous thrombus ...
Xiaolong Li +4 more
wiley +1 more source
Lungs damage in Behçet’s disease
Behçet’s disease (BD) is a systemic vasculitis of unknown origin characterized by ulcerous damage of oral and genital mucosa as well as eyes and skin. Other organs (nervous system, lungs, joints, gastro-intestinal tract) are rarely involved.
Z S Alekberova, R G Goloeva, T V Lapinaa
core +1 more source
Vision-Threatening Behcet’s Disease: Severity of Ocular Involvement Predictors
Purpose. To examine and spot systemic findings commonly associated with a serious form of ocular Behcet’s disease. This could potentially help ophthalmologists categorize their patients based on future risk and plan treatment accordingly.
Mohammed A. Hussein +2 more
doaj +1 more source
Spinal Cord Sarcoidosis Treated With Infliximab
ABSTRACT Isolated spinal cord lesion could be misinterpreted as a demyelinating disease. The diagnosis of sarcoidosis should be in the differential when other indices for a demyelinating disorder are absent. An inadequate response to intravenous steroid therapy should not rule out spinal sarcoidosis as this report confirms the response to intravenous ...
Hussein Moussa +4 more
wiley +1 more source

