Results 161 to 170 of about 13,305,381 (334)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Intermittent theta burst stimulation (iTBS) and inhibitory control training for excess weight treatment: study protocol for a randomized controlled trial (InhibE)

open access: yesBMC Psychology
Background The prevalence of excess weight has increased globally. Despite interventions include targeted goals on essential aspects such as physical activity and diet, their long-term effectiveness remains limited.
Andrea Bernat-Villena   +5 more
doaj   +1 more source

Electrochemical Behavior of Ion Exchange Resin Membrane Electrodes

open access: bronze, 1955
Harold E. Affsprung   +2 more
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

The Etiology, Assessment and Treatment of Compulsive Checking: A Review

open access: yesPsychology Research and Behavior Management
Sisi Guo, Mina Yadegar, Helen Khaw, Susanna Chang UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USACorrespondence: Sisi Guo, Email sisiguo@mednet.ucla.eduAbstract: Checking is the most reported compulsion of Obsessive ...
Guo S, Yadegar M, Khaw H, Chang S
doaj  

Suicidal risk among Chinese parents of autistic children and its association with perceived discrimination, affiliate stigma and social alienation

open access: yesBMC Psychiatry
Background Caring for autistic children becomes challenging and may lead to negative psychological outcomes, even increasing the suicide risk (SR). Researchers have studied the SR among parents of autistic children in Western nations, but little is known
Wan Wang   +5 more
doaj   +1 more source

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