Results 241 to 250 of about 13,305,381 (334)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou+5 more
wiley +1 more source
Effects of psychological resilience on social media information-sharing behavior in older adults: mediating role of technology anxiety and perceived enjoyment. [PDF]
An J+5 more
europepmc +1 more source
THE SEDIMENTATION BEHAVIOR AND MOLECULAR WEIGHT OF PANCREATIC CARBOXYPEPTIDASE
Emil L. Smith+2 more
openalex +1 more source
The Interpretation of the Behavior of the Lower Organisms [PDF]
H. S. Jennings
openalex +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham+21 more
wiley +1 more source
The Role of the Antennae in the Mating Behavior of Female Drosophila [PDF]
Ernst Mayr
openalex +1 more source
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban+12 more
wiley +1 more source
Genetic Evidence of Aberrant Chromosome Behavior in Maize Endosperm
R. A. Emerson
openalex +2 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source