Results 301 to 310 of about 16,785,403 (406)
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
Temporal changes in behavior during the group spawning event of Pacific herring (Clupea pallasii). [PDF]
Seki K+7 more
europepmc +1 more source
エゾヤチネズミ MYODES RUFOCANUS ノ ヒハンショク コタイ ノ テイオン カ デ ノ タイエキセイ メンエキ ハンノウ ノ ヒカク [PDF]
Kusumoto, kaori+1 more
core
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo+2 more
wiley +1 more source
Mechanisms of change in a gender-sensitized health intervention: the mediating role of health self-efficacy. [PDF]
Vassallo JS, Shearson KM, Sharples JM.
europepmc +1 more source
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Comparison of peer and instructor training techniques on waste separation behavior at source amongst female students in Iran. [PDF]
Bayat M, Farzadkia M, Dehdari T.
europepmc +1 more source