Results 161 to 170 of about 228,317 (361)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Moths behaving like butterflies. Evolutionary loss of long range attractant pheromones in Castniid Moths: A Paysandisia archon model

, 2012
Background: In the course of evolution butterflies and moths developed two different reproductive behaviors. Whereas butterflies rely on visual stimuli for mate location, moths use the"female calling plus male seduction" system, in which females release ...
Rosell, Glòria, Miquel A Jiménez, Rosell Pellisé, Glòria, Quero López, Carmen, Acín Viu, Patricia, Guerrero Pérez, Ángel, Sarto i Monteys Víctor, Quero, Carmen, Jiménez, Miquel A., Carmen Quero, Glòria Rosell, Rosell Glòria, Acín Patricia, Guerrero Angel, Acín, Patricia, Guerrero, Ángel, Jiménez Miquel A., Patricia Acín, Sarto, Víctor, Angel Guerrero, Sarto i Monteys, Victor, Miquel A. Jiménez, Quero Carmen, Víctor Sarto i Monteys   +23 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Optical model for deuteron-induced elastic scattering on light nuclei from 3He to 16O

Frontiers in Physics
An optical model analysis is performed for deuteron-induced elastic scattering on light nuclei from 3He to 16O over an extended energy range from 10 to 270 MeV.
Waleed Saleh Alrayashi, S. M. Al-Rawashdeh   +1 more
doaj   +1 more source

The Role a Concept Plays in Science - The Case of Homology [PDF]

, 2003
The present paper gives a description and philosophical analysis of the conceptual variation in the homology concept. It is argued that different homology are concepts used in evolutionary and comparative biology, in developmental biology, and in ...
Brigandt, Ingo
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

An intra- and interspecific study of body size and autotomy as a defense in Orthoptera

, 2008
Autotomy, the ‘voluntary’ shedding of a limb or other body part, is a highly effective escape mechanism to avoid predation or other forms of entrapment. Autotomy, however, comes with costs to locomotion, reproductive behavior, regeneration etc.
Bateman, P.W., Fleming, P.A.
core  

Molecular systematics of marine gregarine apicomplexans from Pacific tunicates, with descriptions of five novel species of Lankesteria

, 2015
The eugregarines are a group of apicomplexan parasites that mostly infect the intestines of invertebrates. The high level of morphological variation found within and among species of eugregarines makes it difficult to find consistent and reliable traits ...
Wakeman, Kevin C., Rueckert, Sonja, Jenke-Kodama, Holger, Leander, Brian S.   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Merkmalsgewichtung in der Systematik : Zeichentheorie, Falsifikationismus und Phylogenetik

, 2002
Vogt L. Merkmalsgewichtung in der Systematik : Zeichentheorie, Falsifikationismus und Phylogenetik. Bielefeld (Germany): Bielefeld University; 2002.In den beiden Postern "Zur Phylogenie der Polychaeta anhand von 18S rDNA Sequenzen" und "Travisia ist ein ...
Vogt, Lars
core