Results 151 to 160 of about 1,857,340 (296)
A Wavelet Approach for Factor-Augmented Forecasting [PDF]
It has been acknowledged that wavelets can constitute a useful tool for forecasting in economics. Through a wavelet multiresolution analysis, a time series can be decomposed into different time-scale components and a model can be fitted to each component
António Rua
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Factor shares, the price markup, and the elasticity of substitution between capital and labor
price markups, factor shares, elasticity of ...
Hector Sala +2 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Five-factor personality dimensions and work behavior
, 2005 Ovim se radom nastojala rasvjetliti uloga dimenzija ličnosti petofaktorskog modela u razumijevanju nekih aspekata radnog ponašanja. U prvom su dijelu rada opisane osnovne pretpostavke i empirijski status petofaktorskog modela, problemi koji se vezuju uz
Nada Krapić, Krapić, Nada
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Altruistic behavior as a costly signal of general intelligence. [PDF]
Unconditional altruism is an enduring puzzle for evolutionary approaches to social behavior. In this paper we argue that costly signaling theory, a well-established framework in biology and economics, may be useful to shed light on the individual ...
Dewitte, Siegfried, Millet, Kobe
core
Development and validation of a scale for the psychological determinants of dietary management behavior in hemodialysis patients during dialysis. [PDF]
PLoS OneWu T +5 more
europepmc +1 more source