Results 101 to 110 of about 8,471,988 (352)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
AgricultureBehavior recognition and multi-object tracking of dairy cows in free-style cow barn environments play a crucial role in monitoring their health status and serve as an essential means for intelligent scientific farming.
Changfeng Wu +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Royal Society Open ScienceScientists and philosophers have long struggled with the question of whether non-human animals experience emotions or consciousness. Yet, it is unclear where the scientific consensus on these topics lies today.
Matthew N. Zipple +3 more
doaj +1 more source
Adaptive-Modeling Multi-Agent Learning System for Video Behavioral Clustering Recognition [PDF]
, 2023 Xingyu Qian +6 more
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A survey of video behavior recognition based on deep learning
Dianxin kexue, 2019 In recent years,the deep learning method of automatic learning features has been continuously explored in the field of video behavior recognition.The traditional behavior recognition methods and the underlying principles of deep learning were outlined ...
Duoduo ZHAO +4 more
doaj
An image dataset for analyzing tea picking behavior in tea plantations
Frontiers in Plant ScienceTea is an important economic product in China, and tea picking is a key agricultural activity. As the practice of tea picking in China gradually shifts towards intelligent and mechanized methods, artificial intelligence recognition technology has become ...
Ru Han +8 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source