Results 181 to 190 of about 11,021,950 (406)

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

The Effect of Two Weight Reduction Maintenance Strategies for Moderately/Mildly Retarded Adults [PDF]

open access: yes, 1986
Thirteen retarded adult subjects were first exposed to a 12-week behavior therapy weight reduction program followed by a ten-month weekly weigh-in. Then the subjects were randomly assigned to an experimental maintenance booster session group (n=7) or a ...
Fox, Robert   +5 more
core   +1 more source

Cognitive-Behavioral Therapy

open access: yes, 2012
Cognitive-behavioral therapy (CBT) encompasses various psychotherapeutic approaches that are rooted in the fundamental principle that a person’s thinking is the prime determinant of emotional and behavioral responses to life situations. The historical influences of CBT can be found in the behavioral approaches: John Watson’s classical conditioning and ...
A. Antonio González-Prendes   +3 more
openaire   +1 more source

Therapy as an NLP Task: Psychologists' Comparison of LLMs and Human Peers in CBT [PDF]

open access: yesarXiv
Wider access to therapeutic care is one of the biggest challenges in mental health treatment. Due to institutional barriers, some people seeking mental health support have turned to large language models (LLMs) for personalized therapy, even though these models are largely unsanctioned and untested. We investigate the potential and limitations of using
arxiv  

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits   +7 more
wiley   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1332-1346, May 2025.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

The Treatment of Hysterical Blindness by Behavior Therapy

open access: bronze, 1974
Yoshiteru Ohno   +5 more
openalex   +1 more source

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