Results 291 to 300 of about 11,698,627 (398)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A Smartphone Application Based on Dialectical Behavior Therapy Skills for Binge Eating Episodes: Study Protocol for a Randomized Controlled Trial. [PDF]

Healthcare (Basel)
Cruz T, Ferreira TB, Safer DL, Duarte C, Martins MV.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intrusive Memory Frequency and Related Inner Tension Following Dialectical Behavior Therapy or Cognitive Processing Therapy for Posttraumatic Stress Disorder: An e-Diary Study.

JMIR Ment Health
Schmitz SE, Ebner-Priemer UW, Kleindienst N, Friedmann F, Bohus M, Steil R, Müller-Engelmann M, Limberger MF, Hartnagel LM, Santangelo P, Priebe K.   +10 more
europepmc   +1 more source

Veterans regaining control; preliminary effects of inpatient Dialectical Behavior Therapy based PTSD treatment. [PDF]

Eur J Psychotraumatol
Wesseling G, Nispeling E, Tholel J, Teunissen S, Thomaes K.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Considerations for the use of dialectical behavior therapy for individuals experiencing oppression. [PDF]

Psychotherapy (Chic)
Oshin LA, Rizvi SL.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Effect of cognitive behavior therapy on abstinence among healthy smokers: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Osong Public Health Res Perspect
Kumar R, Malhotra P, As V, Beniwal K, Charan GS.   +4 more
europepmc   +1 more source