Results 51 to 60 of about 1,916,432 (308)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Motivation in Physical Education Classes: A Self-Determination Theory Perspective [PDF]

, 2009
This paper presents a brief overview of empirical studies in school physical education (PE) that have employed SDT and, where relevant, proposes ideas for future research in this area.
Centers for Disease Control and Prevention, Department of Health, Martyn Standage, Nikos Ntoumanis, Standage, M., Taylor, I.   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Graduate student dissonance: Graduate students of color in a U. S. research university [PDF]

, 2013
This qualitative investigation examined the experiences of a population of graduate students - graduate students of color - in a U. S. research university (a) to indicate reasons for their dilemmas, ambiguities, and decisions about choosing an academic ...
Haley, KJ, Jaeger, AJ, Levin, JS
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Enhancing teachers’ professional competence through licensure tests and intervention: a study on teacher competence and student academic performance in Ethiopia

Discover Education
Teachers’ professional competence is an important factor that has a proven effect on student academic performance and in turn on educational quality. The study aimed at enhancing teachers’ professional competence licensure test, teachers’ competence and ...
Abdulmejid Mohammed Ahmed, Berhanu Nigussie Worku, Zenebe Negewo Ayane   +2 more
doaj   +1 more source

Formula-feeding practice and associated factors among urban and rural mothers with infants 0–6 months of age: a comparative study in Jimma zone Western Ethiopia

BMC Pediatrics, 2019
Background Infants are in a state of rapid development and maturation; the growth rate is most rapid during the first 4 to 6 months of life. Few studies indicated that in developing countries including Ethiopia the prevalence and duration of ...
Lakew Abebe, Mamusha Aman, Shifera Asfaw, Hailay Gebreyesus, Mebrahtu Teweldemedhin, Abebe Mamo   +5 more
doaj   +1 more source

Treatment Effects on Ordinal Outcomes: Causal Estimands and Sharp Bounds

, 2018
Assessing the causal effects of interventions on ordinal outcomes is an important objective of many educational and behavioral studies. Under the potential outcomes framework, we can define causal effects as comparisons between the potential outcomes ...
Dasgupta, Tirthankar, Ding, Peng, Lu, Jiannan   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Effects of fear of failure and peer pressure on academic: motivation among grade 12 students in gedeo zone, South Ethiopia region

Discover Psychology
The present study aimed to examine the effects of fear of failure, and peer pressure on academic motivation among Grade 12 students. Academic motivation is crucial for student success, particularly during the final years of secondary education, when ...
Markos Malimo Setena, Habtamu Disasa Muleta, Abrham Petros Wontamo   +2 more
doaj   +1 more source