Results 101 to 110 of about 2,215,981 (303)

Predicting Generalized Anxiety Disorder Based on Emotion Regulation Deficits, Thought-Action Fusion, and Behavioral Inhibition [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2015
Background & Aims: Generalized anxiety disorder (GAD) can be affected by different emotional, cognitive, and natural factors. The purpose of this study was to predict GAD based on emotion regulation deficits, thought-action fusion, and behavioral ...
Roghayeh Ataie-Moghanloo   +2 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Lifespan changes in the countermanding performance of young and middle aged adult rats

open access: yesFrontiers in Aging Neuroscience, 2016
Inhibitory control can be investigated with the countermanding task, which requires subjects to make a response to a go signal and cancel that response when a stop signal is presented occasionally.
Jonathan Beuk   +4 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Relations between behavioral inhibition, big five personality factors, and anxiety disorder symptoms in non-clinical and clinically anxious children [PDF]

open access: yes, 2012
This study examined the relations between behavioral inhibition, Big Five personality traits, and anxiety disorder symptoms in non-clinical children (n = 147) and clinically anxious children (n = 45) aged 6-13 years.
Leonie J. Vreeke   +5 more
core   +1 more source

Toward a Standardized Test of Fearful Temperament in Primates: A Sensitive Alternative to the Human Intruder Task for Laboratory-Housed Rhesus Macaques (Macaca mulatta)

open access: yesFrontiers in Psychology, 2019
Standardized and sensitive tests to assess differences in temperament among primates housed in captivity are essential for monitoring welfare and improving science outcomes through reduced noise in data.
Emily J. Bethell   +7 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Glucocorticoids, the hippocampus, and behavioral inhibition in the preweanling rat

open access: yes, 1995
Endogenous corticosteroids influence brain development and behavioral expression. In rat pups, a corticosteroid-dependent developmental response is behavioral inhibition, which occurs in situations involving threat.
LK Takahashi
core   +1 more source

Anger Weakens Behavioral Inhibition Selectively in Contact Athletes

open access: yesFrontiers in Human Neuroscience, 2018
Studies have increasingly found that the aggression level of contact athletes is higher than that of non-athletes. Given that higher aggression levels are associated with worse behavioral inhibition and that athletes show better behavioral inhibition ...
Xue Xia, Guanghui Zhang, Xiaochun Wang
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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