Results 121 to 130 of about 622,855 (308)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
ANALISIS TOURISTS’ ON-SITE EXPERIENCE DALAM MEMBENTUK BEHAVIORAL INTENTION :Survei pada wisatawan Malaysia yang berkunjung di Kota Bandung [PDF]
, 2014 Travel and Tourism is one of the largest contributors to the economic growth of the region, no exception in Bandung city. As an international tourist destination in Indonesia, Bandung has a small international tourist repeater compared with the first ...
Majid, Abdul
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Propensity To Continue Service Internationalization - A Model Of Planned Behavior [PDF]
The present study investigates the propensity to continue internationalization by experienced international service providers. Enhancing the cognitive-behavioral root of internationalization process theory (Johanson and Vahlne 1977; 1990), this paper ...
Patterson,Paul G. +3 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Participants’ behavioral intention to re-attend outdoor sport events (Penang, Malaysia) / Siew-Ching Yeoh and Yen-Nee Goh [PDF]
, 2017 There have been many outdoor sports events organized in Malaysia every year. Some of the events have turned out to be one of the major attraction among the participants such as the Penang Bridge International Marathon Run where the participants have been
Goh, Yen-Nee, Yeoh, Siew-Ching
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Influence of Attitude, Subjective Norm and Perceived Behavioral Control on Intention : The Application of Theory Planned Behavior in Choosing Double Degree Program. [PDF]
, 2018 This study is applying the Theory of Planned Behavior as a theoretical framework with aim of choosing double degree program in Muhammadiyah University of Surakarta, Indonesia. Data are collected through questionnaire.
, Dr.Syamsudin, M.M +1 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source