Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Advancing Behavioral Medicine: The International Pursuit of Science for 30 Years. [PDF]
Hoyt MA, Liu R, Zhang CQ.
europepmc +1 more source
Correction to: Advocacy to support climate and health policies: recommended actions for the Society of Behavioral Medicine. [PDF]
europepmc +1 more source
Society of behavioral medicine statement on COVID-19 and rural health. [PDF]
Behrman P +4 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Translational Sleep Science in Behavioral Medicine: Introduction to this Special Issue. [PDF]
Williams N, Trevorrow T.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Behavioral Medicine Can Tackle Cardiovascular Disease Risk and Burden: A Call for New Priorities. [PDF]
Burg MM +5 more
europepmc +1 more source
Effectiveness of a behavioral medicine intervention in physical therapy on secondary psychological outcomes and health-related quality of life in exercise-based cardiac rehabilitation: a randomized, controlled trial. [PDF]
Borg S +5 more
europepmc +1 more source

