Results 231 to 240 of about 251,773 (308)

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Behavioral and Cognitive Strategies in Pediatric Dentistry: Current Concepts in Anxiety and Fear Management. [PDF]

Cureus
Alfadhli HA, Deka Q, Samanta I, Masne SP, Tripathi P, Sriranjan P.   +5 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Correction: The realism of behavioral theory-based vs. non-theory-based AI agents during a simulated infant formula shortage. [PDF]

Front Artif Intell
Desens L, Walling B, O'Neill R, Howard V, Giammarino M, Scannell D, Kemble A, Wilkerson T, Nhial N, Elson SB, Leahy M, Rosen S.   +11 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Behavior of college students in public health emergencies based on IMB model. [PDF]

Medicine (Baltimore)
Li L, Mei Y, Huang Y, Zhou L, Zeng G, Huang H.   +5 more
europepmc   +1 more source

A Hybrid Model for Copper Futures Price Forecasting Utilizing Complexity-Aware Variational Mode Decomposition and Reconstruction and Multi-Behavior-Triggered Interaction Modeling. [PDF]

Entropy (Basel)
Li Y, Liu D.
europepmc   +1 more source

Effectiveness of scenario-based high-fidelity simulation training on management of medical emergencies in dental settings: a theory-based intervention with a long-term follow-up. [PDF]

BMC Med Educ
Alawaji YN, Alharthy NA, Alghamdi A, Alshibani A, Binhotan M, Alqahtani H, Albalawi F, Alshehri A, Aboalela A, Altuwaijri SH, Kalagi SA, Alfadley A.   +11 more
europepmc   +1 more source

Improving Context-Aware Personalized Nudging: Using Wearable Sensors to Reduce Sedentary Behavior. [PDF]

Dela J Public Health
Rahman T, Vemuri A, Firkin CJ, Bodt B, Orsega-Smith E, Dominick GM, Decker K.   +6 more
europepmc   +1 more source

Public opinion dissemination simulation based on large language model multi-agent systems. [PDF]

Sci Rep
Lan H, Hu H, Guo PC, Huang Q.
europepmc   +1 more source