Results 71 to 80 of about 646,611 (300)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Design for energy conservation intervention: lessons learned from weight loss intervention [PDF]

Self-monitoring behavioral interventions for weight loss and energy conservation share some common ground in terms of their intervention approach and feedback design and delivery.
Kuo, Pei-Yi (Patricia)
core   +1 more source

Outcome Measures of Behavioral Weight Loss Programs in Perimenopause [PDF]

Southern Medical Journal, 2014
Obesity and being overweight are associated with many comorbid conditions and are major contributing factors to cardiovascular disease. The increased proportion of overweight and obese people in Western societies has been attributed largely to behaviors that include sedentary lifestyle and dietary excess.
Naira, Zargarian, Ruth, Lindquist, Cynthia R, Gross, Diane, Treat-Jacobson   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Subjective experiences of physical activity and forecasting bias during behavioral weight loss

Obesity Science & Practice, 2022
Introduction Engagement in physical activity (PA) is a critical component of behavioral weight loss (BWL) treatment. Subjective experiences surrounding PA may shape exercise decisions and need to be further understood within a BWL sample.
Nicole T. Crane, Mary K. Martinelli, Evan M. Forman, Meghan L. Butryn   +3 more
doaj   +1 more source

Morbidity and Mortality ofVery Low Birth Weight Infant Graduates of a Level Three Neonatal Intensive Care Unit [PDF]

, 2007
Purpose: To describe the morbidity and mortality of very low birth weight (VLBW) infant graduates of a level three neonatal intensive care unit (NICU) in a medically underserved population.
Cortes, Maria
core   +1 more source

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]

, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
A Bosutti, A Jellema, A Laugeray, A Peters, A Rossi-George, A Schaffner, AA Wadee, AH Swiergiel, AJ Grossberg, AL Hassett, AL Lacerda, AM Myint, AN van den Pol, AS El-Radhi, AS Wrynn, AY Lai, B Leonard, B Owe-Larsson, BE Leonard, BE Leonard, BG Charlton, BL Hart, Brian Leonard, C Celik, C Nathan, C Song, C Song, C Song, C Song, C Song, CA Stockmeier, Cai Song, CL Raison, D Brustolim, D Wang, DK Kinney, EA Stone, ES Wohleb, F Frenois, F Kapczinski, F Moroni, G Anderson, G Werner-Felmayer, George Anderson, GM MacQueen, GR Steinberg, H Anisman, H Anisman, H Nakanishi, HC Liu, HP Kopp, I Kirsch, IK Lampe, IR Bell, J Hannestad, J Steiner, JC O'Connor, JE Bower, JE Holmes, JL Rausch, JM Twenge, KJ Jung, KJ Tracey, KS Kendler, L MacDonald, L Qin, L Toker, LE Goehler, LE Goehler, Lisa Goehler, LJ Williams, LM Harden, LV Kessing, LV Kessing, M Adib-Conquy, M Berk, M Berk, M Berk, M Berk, M Catena-Dell'Osso, M Kauer-Sant'Anna, M Koenigs, M Kubera, M Kubera, M Lyte, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, M Maes, MB Hennessy, MB Howren, MC McKinnon, MC Wichers, MC Wichers, MC Wichers, MD Burton, ME Sublette, Michael Berk, Michael Maes, MJ Hoes, MJ Kluger, MJ Kluger, MJ Sharman, MP Szuba, MT Berlim, N Castanon, N Castex, NA Harrison, O Caliyurt, O Takikawa, P Gorwood, P Taepavarapruk, P Videbech, Piotr Gałecki, R Dantzer, R Medzhitov, R Roubenoff, R Yirmiya, RC Bone, RH Straub, RJ Boland, RK Jewkes, RK Kumar, RM Post, RPA Gaykema, RPA Gaykema, RPA Gaykema, RW Johnson, S Bonaccorso, S Bonaccorso, S Cunningham-Rundles, S Lacosta, S Rantala, S-M Park, SC Strijdom, SD Burdette, SE Møller, SF Maier, SM Antelman, SM Jancsár, SM O'Brien, SM Sylvén, T Hochstrasser, T Liukkonen, T Sato, T Tuma, TA Lennie, TC Olde Hartman, TM Piser, V Gabbay, WC Drevets, WS Yang, Y Dowlati, Y Huang, Y Jiang, Y Kawasaki, Y Liu, Z Pavlovićc, Z Xia   +189 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Traditional and cyberbullying victimization as correlates of psychosocial distress and barriers to a healthy lifestyle among severely obese adolescents : a matched case-control study on prevalence and results from a cross-sectional study [PDF]

, 2014
Background: Obese youth are at increased risk for peer victimization, which may heighten their risk of psychosocial problems and physical activity avoidance, and lower the effectiveness of professional and lifestyle weight-loss initiatives.
De Bourdeaudhuij, Ilse, Deforche, Benedicte, DeSmet, Ann, Hublet, Anne, Stremersch, Evi, Tanghe, Ann   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source