Results 91 to 100 of about 4,902,943 (336)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Gender Gaps In Voter's Behaviour In Modern Ukraine: Factors And Influence [PDF]
The article deals with the important and insufficiently studied problem of specificity of the gender influence on electors' orientations in modern Ukraine.
Dziuba, N. (Nataliia)
core
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Playing the piano with a robotic third thumb: assessing constraints of human augmentation
Contemporary robotics gives us mechatronic capabilities for augmenting human bodies with extra limbs. However, how our motor control capabilities pose limits on such augmentation is an open question. We developed a Supernumerary Robotic 3rd Thumbs (SR3T)
Ali Shafti+4 more
doaj +1 more source
MIA HALL’S BEHAVIOUR CHANGE IN GAYLE FORMAN’S IF I STAY [PDF]
This final project analysis Gayle Forman’s novel entitled: If I Stay. The purpose of this final project is to analysis the behaviour change of the main character, Mia Hall.
Kusumaningrum, Kusumaningrum
core +1 more source
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa+8 more
wiley +1 more source
Applications of the theory of planned behaviour to drivers' speeding behaviour [PDF]
The theory of planned behaviour (TPB; Ajzen, 1985, 1988, 1991) provides apotentially useful approach for investigating the links between drivers' attitudes andbehaviour and for informing road safety interventions that aim to promote 'safe' driving.
Armitage, C.J.+2 more
core
Interviews of deshopping behaviour: An analysis of theory of planned behaviour [PDF]
Research reveals alarming results on the prevalence of the dishonest consumer behaviour known as deshopping. Deshopping is the “deliberate return of goods for reasons other than actual faults in the product, in its pure form premeditated prior to and ...
Dennis, C, King, T
core +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Functional neuroimaging has contributed substantially to understanding brain function but is dominated by group analyses that index only a fraction of the variation in these data.
Hannah S. Savage+7 more
doaj +1 more source