Results 61 to 70 of about 5,436,139 (290)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

An ontology-based modelling system (OBMS) for representing behaviour change theories applied to 76 theories [version 1; peer review: 2 approved]

Wellcome Open Research, 2020
Background: To efficiently search, compare, test and integrate behaviour change theories, they need to be specified in a way that is clear, consistent and computable.
Joanna Hale, Janna Hastings, Robert West, Carmen E. Lefevre, Artur Direito, Lauren Connell Bohlen, Cristina Godinho, Niall Anderson, Silje Zink, Hilary Groarke, Susan Michie   +10 more
doaj   +1 more source

Developing a Mammalian Behaviour Ontology [PDF]

, 2009
The use of the Entity + Quality (EQ) model in phenotypic descriptions is dependent on the use of specialised domain ontologies to define the entity under observation.
Ann-Marie Mallon, John M. Hancock, Tim Beck   +2 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Rapid modulation of choice behavior by ultrasound on the human frontal eye fields

Nature Communications
A fundamental challenge in neuroscience is establishing causal brain-function relationships with spatial and temporal precision. Transcranial ultrasonic stimulation offers a unique opportunity to modulate deep brain structures non-invasively with high ...
S. Farboud, B. R. Kop, R. S. Koolschijn, S. L. Y. Walstra, J. P. Marques, A. Chetverikov, W. P. Medendorp, L. Verhagen, H. E. M. den Ouden   +8 more
doaj   +1 more source

Assessing the Emotional Response in Social Communication: The Role of Neuromarketing

Frontiers in Psychology, 2021
Social advertising is designed to have an impact on the behavior of the target audience to improve the welfare of both the individuals and the society.
Margherita Zito, Margherita Zito, Alessandro Fici, Alessandro Fici, Marco Bilucaglia, Marco Bilucaglia, Francesco S. Ambrogetti, Vincenzo Russo, Vincenzo Russo   +8 more
doaj   +1 more source

Internal charge behaviour of nanocomposites [PDF]

, 2004
The incorporation of 23 nm titanium dioxide nanoparticles into an epoxy matrix to form a nanocomposite structure is described. It is shown that the use of nanometric particles results in a substantial change in the behaviour of the composite, which can ...
Alison J, Artbauer J, Bambery K R Fleming R J, Chapman D L, Crine J-P, Dissado L A, Dissado L A, Frechette M F, Griseri V, Henk P O, Henk P O Henriksen M Holbell J T Iqbal J, J Keith Nelson, John C Fothergill, Jonscher A K, Kawamoto A, Lewis T J, Mason J H, Nelson J K, Nelson J K Fothergill J C Dissado L A Peasgood W, Sabuni H, van Turnhout J   +20 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Optimal inference with suboptimal models:Addiction and active Bayesian inference [PDF]

, 2014
When casting behaviour as active (Bayesian) inference, optimal inference is defined with respect to an agent's beliefs - based on its generative model of the world.
Adams, Adams, Bechara, Beck, Beck, Belin, Berke, Berridge, Berridge, Bickel, Bishop, Blum, Blum, Blum, Bowers, Bowers, Brighton, Cain, Charness, Christoph Mathys, Clark, Clark, Comings, Conant, Daunizeau, Daw, Dayan, Dayan, Diana, Dolan, Doyon, Edwards, Everitt, Everitt, Eysenck, FitzGerald, Friedrich Wurst, Friston, Friston, Friston, Friston, Friston, Friston, Geisler, Gigerenzer, Gillan, Graybiel, Grether, Griffiths, Griffiths, Henden, Hommer, Jones, Kahnemann, Karl Friston, Kersten, Knill, Lee, MacKay, Mahmood, Maia, Martin Kronbichler, Miedl, Montague, Monterosso, Pellicano, Peters, Peters, Philipp Schwartenbeck, Pouget, Ray Dolan, Redish, Redish, Robinson, Schwartenbeck, Simon, Simon, Stephan, Story, Sutton, Taber, Tenenbaum, Thomas H.B. FitzGerald, Tversky, Tversky, Weiss, Whalley, Willuhn, Wolpert, Yu   +89 more
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source