Results 231 to 240 of about 2,982,565 (345)

Bridging the gap between human behaviour and animal welfare: A study on human behaviour change and body condition scoring of suckler cows. [PDF]

Anim Welf
Jessiman L, Naydani CJ, Rutherford KM, Turner SP.   +3 more
europepmc   +1 more source

Additional file 1 of Facilitating a complex behaviour-change intervention: healthcare professionals’ accounts of their journeys to competence and confidence

Ruth I. Hart, Christina Sheehan, Debbie Brewin, Kieran Ayling, Kavita Vedhara, Fran Game, Julia Lawton   +6 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

From Dismissal to Partnership: Patient Experiences of Recurrent Urinary Tract Infection Healthcare Informed by the Theoretical Domains Framework and Behaviour Change Theory. [PDF]

Health Expect
Newlands AF, Kramer ML, Snuggs S, Finlay KA.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Enhancing Engagement with Stop Smoking Services among Lower Socioeconomic Groups across the UK: A Qualitative Study using the Behaviour Change Wheel. [PDF]

Nicotine Tob Res
Smith P, Dahlby L, Plotnikova E, Williams RB, Thorley R, Murray R, Dobbie F, Langley T, Bogdanovica I, Brain K, Jayes L.   +10 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Shared decision-making and behaviour change collide: an analysis of consultations discussing clinical trial recruitment. [PDF]

Trials
Stephen A, Matuluko A, Carroll K, Coffey T, Lawrie L, Sherratt F, Hudek N, Lorencatto F, Presseau J, Marlin S, Richards DP, Brehaut J, Gillies K.   +12 more
europepmc   +1 more source

From cave geomorphology to Palaeolithic human behaviour: speleogenesis, palaeoenvironmental changes and archaeological insight in the Atxurra‐Armiña cave (northern Iberian Peninsula)

, 2020
Martín Arriolabengoa, Iñaki Intxaurbe, Ma Ángeles Medina‐Alcaide, Olivia Rivero, Joseba Ríos-Garaizar, Iñaki Líbano, Peru Bilbao, Arantza Aranburu, Hai Cheng, R. Lawrence Edwards, Diego Gárate Maidagán   +10 more
openalex   +2 more sources