Results 221 to 230 of about 359,828 (296)

Transforming multimorbidity care: Organizational barriers and provider behaviour in type 2 diabetes and cardiovascular disease. [PDF]

Br J Health Psychol
Brown JE, Umeh FK, Lotto R, Madroumi R, Jones I, Rashidi A, Newson L.   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Associations of Emotion Regulation Difficulties, Psychological Well-Being, and Life Satisfaction with Suicidal Ideation and Suicidal Behaviour Among University Students in Indonesia: A Cross-Sectional Study. [PDF]

J Multidiscip Healthc
Dwidiyanti M, Windarwati HD, Lestari R, Nihayati HE, Irmansyah I, Maharani A, Brooks H, Hikmat R.   +7 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

"It's just one piece of the puzzle…": practitioners' perspectives on the use of sterilisation in the management of free-roaming dog populations. [PDF]

Front Vet Sci
Collinson A, Brennan ML, Dean RS, Stavisky J.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Feasibility Trial of a Health Behaviours Promotion Group for Youth at Clinical High Risk for Psychosis. [PDF]

Early Interv Psychiatry
Ruiz-Yu B, Diaz T, Hernandez D, Zinberg J, Miklowitz DJ, Bearden CE.   +5 more
europepmc   +1 more source

The Roles of Volunteer Tourism in Changing Tourist Behaviour and Local Community Well-being in Indonesia (Case Study of Tour Operator Wanderlust Indonesia)

, 2021
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

'Moving People up the Sympathy Spectrum': Building Hypotheses About How Abortion Values Clarification and Attitude Transformation (VCAT) Can Change Healthcare Provider Behaviours. [PDF]

Health Expect
Makleff S, Van Rensburg C, Merner B, Wollum A, Keogh L.   +4 more
europepmc   +1 more source