Results 101 to 110 of about 84,332 (315)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mental illness knowledge and the intention to seek psychiatric treatment among college athletes: use of a two-axis matrix to assess a new method of mental health support

BMJ Open
Objectives This study examined college athletes’ knowledge of mental illness and their intention to seek psychiatric treatment.Design A cross-sectional design.Setting College athletes in Japan.Participants Japanese college athletes (n=351; 255 men, 96 ...
Tsuneyoshi Ota, Miyuki Nakamura, Yujiro Kawata, Yuka Murofushi, Nobuto Shibata   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Relationships between attitudes, intentions, and behaviour among college students in the field of information ethics

Discover Education
This study explores the complex interrelationships among cognitive constructs—namely attitudes, intention, and behaviour—within the domain of information ethics in information technology, focusing on a sample of undergraduate students in Oman.
Maryam Nasser AL-Nuaimi
doaj   +1 more source

Embracing sustainability on Indian roads: exploring the influence of personality factors in fostering green transportation behaviour

International Journal of Sustainable Energy
Green consumption is gaining prominence across domains to negate the ecological footprint of humans. Focusing exclusively on the green mobility segment, the study attempts to analyze the impact of ‘Big Five’ personality factors on adoption behaviour and ...
Amrutha Shetty, M. Rizwana
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Implementation intentions and health behaviour

, 2005
published
Sheeran, Paschal, Milne, Sarah, Webb, Thomas L., Gollwitzer, Peter M.   +3 more
openaire   +2 more sources

PREDICTING WHISTLE-BLOWING INTENTION AMONG SUPERVISORS IN MALAYSIA [PDF]

The function of whistle-blowing as an effective internal control mechanism has long been accepted around the globe. Several individual factors have been considered as predictive variables of whistle-blowing intention.
Robert Evans, Jeremy Galbreath, Nadzri Ab Ghani   +2 more
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