Results 71 to 80 of about 864,495 (308)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Maintenance management and operational support as services in reconfigurable manufacturing systems [PDF]

, 2009
Emergent architectures and paradigms targeting reconfigurable manufacturing systems increasingly rely on intelligent models to maximize the robustness and responsiveness of modern installations.
Barata, José, Leitão, Paulo, Ribeiro, Luis, Silvério, Nelson   +3 more
core   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Evolutionarily conserved mechanisms for the selection and maintenance of behavioural activity [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2015
Survival and reproduction entail the selection of adaptive behavioural repertoires. This selection manifests as phylogenetically acquired activities that depend on evolved nervous system circuitries. Lorenz and Tinbergen already postulated that heritable behaviours and their reliable performance are specified by genetically determined programs. Here we
Vincenzo G. Fiore, Raymond J. Dolan, Nicholas J. Strausfeld, Frank Hirth   +3 more
openaire   +6 more sources

Efficient synchronization of structurally adaptive coupled Hindmarsh-Rose neurons

, 2011
The use of spikes to carry information between brain areas implies complete or partial synchronization of the neurons involved. The degree of synchronization reached by two coupled systems and the energy cost of maintaining their synchronized behaviour ...
d'Anjou, A, Moujahid, A, Torrealdea, F, Torrealdea, FJ   +3 more
core   +1 more source

Visualization of the modeled degradation of building flooring systems in building maintenance [PDF]

, 2014
The development of a maintenance programme for construction projects is a highly complex and data intensive undertaking. This exercise is characterised by the lack of relevant data on the one hand and the overwhelming amount of extraneous data on the ...
Akintoye, Al-Hajj, Alda, Aouad, Apelt, Arayici, Aydinalp, Barker, Barley, Baumann, Bromilow, Capper, Card, Chapin, Chen, Chinyio, Dawood, Dreyfuss, Finnveden, Flanagan, Flanagan, Froese, Gil, Griffin, Hall, Hall, Haymaker, Holness, Jha, Jones, Jones, Jordan, Kamat, Kamat, Kang, Keoleian, Khosrowshahi, Khosrowshahi, Khosrowshahi, Krygiel, Kuhner, Lang, Lapin, Lipman, Martinez-Ortiz, Nardi, Ng, Olofsson, Pettit, Pitts, Puntenney, Rangaraju, Rapp, Rekapalli, Rhodes, RICS, Robinson, Robinson, Rosenman, Russell, Schensul, Scheuer, Shah, Shen, Sommer, Spedding, Spence, Stone, Sustainable Energy Management and the Built Environment (SEMBE), Tregenza, Waheed, WCED, Whitehead, Wilcox, Wordsworth, Zabalza Bribián, Zhang   +76 more
core   +3 more sources

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

A predation cost to bold fish in the wild

Scientific Reports, 2017
Studies of predator-mediated selection on behaviour are critical for our understanding of the evolution and maintenance of behavioural diversity in natural populations.
Kaj Hulthén, Ben B. Chapman, P. Anders Nilsson, Lars-Anders Hansson, Christian Skov, Jakob Brodersen, Jerker Vinterstare, Christer Brönmark   +7 more
doaj   +1 more source

Adaptive behavioural syndromes due to strategic niche specialization

BMC Ecology, 2007
Background Behavioural syndromes, i.e. consistent individual differences in behaviours that are correlated across different functional contexts, are a challenge to evolutionary reasoning because individuals should adapt their behaviour to the ...
Bergmüller Ralph, Taborsky Michael
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source