Results 81 to 90 of about 4,013,179 (303)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

EFFECT OF STOCKING DENSITY IN GROWING PIGS I. BEHAVIOUR PATTERN [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 1998
A study was designed to find out whether there was any change in the pattern of behaviour in pigs due to change in stocking densities. Aggressive behaviour was measured by counting the number of threats (10.24 ± 0.706, 12.65 ± 0.716 and 15.21 ± 0.775 at
Leena Anil, T.G. Rajagopalan, S.S. Anil
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Tourist attractions as a moderating element in explanatory models for loyalty development

open access: yesTourism & Management Studies, 2014
Many studies have analysed the impact of destination image on tourist satisfaction and loyalty, including different mediating variables, both affective and cognitive. This article will attempt to determine whether the representative model of visitors'
Manuel Rey-Moreno   +2 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Bicycle helmets and risky behaviour : A systematic review [PDF]

open access: yes, 2019
A long-standing argument against bicycle helmet use is the risk compensation hypothesis, i.e., increased feelings of safety caused by wearing a helmet results in cyclists exhibiting more risky behaviour. However, past studies have found helmet wearing is
Radun, Igor,   +8 more
core   +1 more source

Modelling and estimation of tensile behaviour of polylactic acid parts manufactured by fused deposition modelling using finite element analysis and knowledge-based library

open access: yesVirtual and Physical Prototyping, 2018
With the rise of the Fused Deposition Modelling (FDM) industry, a better understanding of the relationship between FDM process parameters and mechanical behaviour —especially tensile behaviour —of designed parts is needed to enable development of ...
Xunfei Zhou   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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