Results 101 to 110 of about 417,101 (218)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

That ‘mushy boxed fog feeling’: dental students’ evaluations of the social and behavioural sciences in dental education

open access: yesMedEdPublish, 2016
This article documents the experiences of two dental educators with responsibility for teaching the Social and Behavioural sciences components of an undergraduate dental programme in the United Kingdom (UK). Many dental undergraduates struggle to see the
Patricia Neville, Andrea Waylen
doaj  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

The BSSO Foundry: A community of practice for ontologies in the behavioural and social sciences [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research
There has been a rapid expansion in the quantity and complexity of data, information and knowledge created in the behavioural and social sciences, yet the field is not advancing understanding, practice or policy to the extent that the insights warrant ...
Paulina Schenk   +12 more
doaj  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Behavioural Conformances based on Lax Couplings [PDF]

open access: yesarXiv
Behavioural conformances -- e.g. behavioural equivalences, distances, preorders -- on a wide range of system types (non-deterministic, probabilistic, weighted etc.) can be dealt with uniformly in the paradigm of universal coalgebra. One of the most commonly used constructions for defining behavioural distances on coalgebras arises as a generalization ...
arxiv  

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