Results 111 to 120 of about 417,101 (218)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Uncovering influence of football players' behaviour on team performance in ball possession through dynamical modelling [PDF]

arXiv
A quest for uncovering influence of behaviour on team performance involves understanding individual behaviour, interactions with others and environment, variations across groups, and effects of interventions. Although insights into each of these areas have accumulated in sports science literature on football, it remains unclear how one can enhance team
arxiv  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Prevention and Treatment of Suicidal Behaviour: From Science to Practice. Edited by Keith Hawton. Oxford University Press. 2005. 400 pp.US$69.50 (pb). ISBN 0198529767 [PDF]

, 2007
Clare Nolan
openalex   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Understanding the information behaviours of carers of people with dementia: A critical review of models from information science [PDF]

, 2008
Juliet Harland, Peter A. Bath
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Social determinants of hazardous alcohol use in a Ugandan population cohort

Global Health Action
Background There is a limited population-based data on hazardous alcohol use and associated social determinants in many African countries. Objectives To examine patterns of hazardous alcohol use across a range of social determinants of health in Uganda ...
Leo Ziegel, Carl Fredrik Sjöland, Erinah Nabunya, Robert Bulamba, Emmanuel Kyasanku, Stephen Mugamba, Godfrey Kigozi, Alex Daama, Grace Kigozi, Amanda P. Miller, Anna-Clara Hollander, Anders Hammarberg, Fred Nalugoda, Anna Mia Ekström   +13 more
doaj   +1 more source

How evolutionary behavioural sciences can help us understand behaviour in a pandemic. [PDF]

Evol Med Public Health, 2020
Arnot M, Brandl E, Campbell OLK, Chen Y, Du J, Dyble M, Emmott EH, Ge E, Kretschmer LDW, Mace R, Micheletti AJC, Nila S, Peacey S, Salali GD, Zhang H.   +14 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source