Results 141 to 150 of about 6,486,296 (378)
A Theory of Personalised Nudging: Integrating Heterogeneity and Behavioural Science into Political Decision-Making [PDF]
, 2020 Stuart Mills
openalex
Citizen science for monitoring seasonal-scale beach erosion and behaviour with aerial drones [PDF]
, 2021 Nicolas Pucino +4 more
openalex +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Detrimental effects of sanctions on human altruism [PDF]
The existence of cooperation and social order among genetically unrelated individuals is a fundamental problem in the behavioural sciences. The prevailing approaches in biology and economics view cooperation exclusively as self-interested behaviour ...
Bettina Rockenbach, Ernst Fehr
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
THE CONCEPT OF COMPARISON INCOME: AN HISTORICAL PERSPECTIVE [PDF]
Theories of social comparison have a long presence in the social sciences and have provided many useful insights. In economics, the idea of comparison, aspiration or relative income belongs to this theoretical framework.
Drakopoulos, Stavros A.
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Social determinants of hazardous alcohol use in a Ugandan population cohort
Global Health ActionBackground There is a limited population-based data on hazardous alcohol use and associated social determinants in many African countries. Objectives To examine patterns of hazardous alcohol use across a range of social determinants of health in Uganda ...
Leo Ziegel +13 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Testes size, testosterone production and reproductive behaviour in a natural mammalian mating system [PDF]
, 2012 1. Testosterone (T) is a key mediator in the expression of numerous morphological and behavioural traits in mammals, but the factors underlying individual variation in circulating T levels are poorly understood. 2.
Lincoln, Gerald A. +5 more
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