Results 151 to 160 of about 6,486,296 (378)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The ethics of using behavioural change science in practice [PDF]

Myra Forster‐van Hijfte
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The Incidence of Sports-Related Concussion in Children and Adolescents: A Systematic Review and Meta-Analysis

Sports Medicine - Open
Background Sport-related concussions (SRC) are a concern for young athletes due to the potential for long-term health problems. This systematic review and meta-analysis aimed to provide a comprehensive overview of the literature exploring SRC incidence ...
Veronica Ingram, Megan Fielding, Laura A. M. Dunne, Stefan Piantella, Jonathon Weakley, Rich D. Johnston, Thomas B. McGuckian   +6 more
doaj   +1 more source

Information-related behaviour as meaning-making processes: a study of science centre visitors

, 2020
Mette Skov, Marianne Lykke
openalex   +1 more source

Is there enough behaviour change science in nutrition and dietetics curricula in Australia and New Zealand? A descriptive study [PDF]

, 2021
Roshan R. Rigby, Lauren Williams, Lauren Ball, Kyra Hamilton, Lana Mitchell   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Applying behavioural science to increase uptake of the NHS Health Check: a randomised controlled trial of gain- and loss-framed messaging in the national patient information leaflet [PDF]

, 2019
Natalie Gold, Caroline Durlik, Jet G. Sanders, Katherine Thompson, Tim Chadborn   +4 more
openalex   +1 more source

From basic science to clinical practice: Do Cognitive Behavioural Therapy tasks benefit from enhanced episodic specificity?

, 2022
Laura Marsh, Shivam Patel, Caitlin Hitchcock, Alicia Smith, Melody So, Tim Dalgleish, Harriet Armstrong, Rachel Elliott, Edward Watkins, Michelle Leanne Moulds   +9 more
openalex   +1 more source