Results 61 to 70 of about 417,101 (218)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Does the opinion of the therapeutic team match with psychometric measures during the course of eating disorders?

Nutrición Hospitalaria, 2013
Introduction: Is there a group of psychometric variables, which correlates with the criteria of an interdisciplinary team about the course of ED?
I. Jáuregui-Lobera, O. Garrido-Casals, M. J. Santiago, P. Bolaños-Ríos, I. Ruiz-Prieto   +4 more
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Service Development for Behavioural Addictions: AIIMS Experience

Annals of the National Academy of Medical Sciences (India), 2017
The concept of behavioural addiction is relatively new. The growing recognition of the behavioural addictions globally and increasing clinical queries catalysed the ongoing deliberations on setting up services for addressing behavioural addictions at the
Yatan Pal Singh Balhara, Rachna Bhargava, Rakesh K. Chadda   +2 more
doaj   +1 more source

Analogue-digital systems and the modular decomposition of physical behaviour [PDF]

arXiv, 2018
We take a fresh look at analogue-digital systems focussing on their physical behaviour. We model a general analogue-digital system as a physical process controlled by an algorithm by viewing the physical process as physical oracle to the algorithm, generalising the notion of Turing.
arxiv  

Behavioural equivalences for coalgebras with unobservable moves [PDF]

, 2014
We introduce a general categorical framework for the definition of weak behavioural equivalences, building on and extending recent results in the field. This framework is based on parametrized saturation categories, i.e. categories whose hom-sets are endowed with complete orders and a suitable iteration operators; this structure allows us to provide ...
arxiv   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Academic procrastinators, strategic delayers and something betwixt and between: An interview study

Frontline Learning Research, 2015
The study explored university undergraduates’ dilatory behaviour, more precisely, procrastination and strategic delaying. Using qualitative interview data, we applied a theory-driven and person-oriented approach to test the theoretical model of ...
Sari Lindblom-Ylänne, Emmi Saariaho, Mikko Inkinen, Anne Haarala-Muhonen, Telle Hailikari   +4 more
doaj   +1 more source

Endofunctors modelling higher-order behaviours [PDF]

arXiv, 2016
In this paper we show how the abstract behaviours of higher-order systems can be modelled as final coalgebras of suitable behavioural functors. These functors have the challenging peculiarity to be circularly defined with their own final coalgebra. Our main contribution is a general construction for defining these functors, solving this circularity ...
arxiv