Results 81 to 90 of about 417,101 (218)

Food choices coping strategies of eating disorder patients´ parents: what happens when both mother and father work?

open access: yesNutrición Hospitalaria, 2013
Objective: Recently, it has been reported that food choices of relatives of eating disorder (ED) patients are not adequate having in mind a healthy model of eating habits.
I. Jáuregui-Lobera   +3 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Coping, stress and suicide ideation in the South African Police Service in the Eastern Cape

open access: yesSouth African Journal of Economic and Management Sciences, 2003
The objective of this research is to determine the relationship between coping and stress on the one hand and suicide ideation among police members on the other. A cross-sectional survey design was used.
R Meyer, S Rothmann, J Pienaar
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Strengths and limits of behaviour change to foster the green transition

open access: yesField Actions Science Reports, 2022
Behavioural approaches increasingly tend to be seen as one of the “go-to” approaches when it comes to solving environmental issues: to address energy and water consumptions, improve agriculture practices, preserve biodiversity, reduce GHG’s emissions ...
Liam Smith
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

BRAVO - a Workflow for Improving Rating Reliability in Behavioural Research

open access: yesPsychological Topics
Reliability assessments are a quality control protocol commonly employed in fields of research that deal with video-recorded behavioural data. During these assessments, the same sample of videos is coded (at least) twice by the same researcher ...
Damien Neadle   +3 more
doaj  

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