Results 141 to 150 of about 42,068 (310)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Empathic responses to unknown others are modulated by shared behavioural traits. [PDF]

Sci Rep, 2020
Anders S, Beck C, Domin M, Lotze M.
europepmc   +1 more source

Exploration behaviour in a different light: testing cross-context consistency of a common personality trait

, 2016
Lisa Arvidsson, Frank Adriaensen, Stefan Van Dongen, Nils De Stobbeleere, Erik Matthysen   +4 more
openalex   +1 more source

The Role of Big 5 Personality Traits in Determining Ethical Behaviour for Hospitality Industry Employees’ in Malaysia

, 2020
Nor Sofiatul Akma Jamaludin, Patrick Mehon   +1 more
openalex   +2 more sources

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Schizotypy, emotional–behavioural problems and personality disorder traits in a non-clinical adolescent population

, 2011
Eduardo Fonseca‐Pedrero, Serafín Lemos Giráldez, Mercedes Paíno, José Muñiz   +3 more
openalex   +2 more sources

Trait Impulsivity Influences Behavioural and Physiological Responses to Threat in a Virtual Environment [PDF]

, 2023
Christopher Baker, Stephen Fairclough, Ruth Ogden, Rachel Barnes, Jessica Tootill   +4 more
openalex   +1 more source

Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations

Advanced Science, EarlyView.
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl, Nandan Haloi, Marta Carroni, Shengpan Zhang, Quentin James Sattentau, Erdinc Sezgin, Lucie Delemotte, Rebecca J. Howard   +7 more
wiley   +1 more source

Sublethal and transgenerational effects of dinotefuran on biological parameters and behavioural traits of the mirid bug Apolygus lucorum. [PDF]

Sci Rep, 2020
Lu Z, Dong S, Li C, Li L, Yu Y, Men X, Yin S.   +6 more
europepmc   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source