Results 121 to 130 of about 352,809 (296)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Do bells affect behaviour and heart rate variability in grazing dairy cows?

open access: yesPLoS ONE, 2015
In alpine regions cows are often equipped with bells. The present study investigated the impact of wearing a bell on behaviour and heart rate variability in dairy cows.
Julia Johns, Antonia Patt, Edna Hillmann
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). [PDF]

open access: yes, 2009
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic association studies are contradictory.
Belinda Martin   +12 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Intra-Individual Behavioural Variability: A Trait under Genetic Control. [PDF]

open access: yesInt J Mol Sci, 2020
Henriksen R   +6 more
europepmc   +1 more source

Computer-Based Formative Assessment : Variables Influencing Feedback Behaviour [PDF]

open access: yes, 2013
Assessment can be used to stimulate and direct student learning. This refers to the formative function of assessment. Formative assessments contribute to learning by generating feedback. Here, feedback is conceptualised as information about learners actual state of performance intended to modify their thinking or behaviour for the purpose of improved ...
openaire   +2 more sources

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Fear in horses [PDF]

open access: yes, 2006
Fear is generally considered to be an undesirable emotional state that may reduce welfare, growth and reproductive performance in animals. Fear in horses is additionally problematic, because fear reactions can cause serious injury to both horse and human.
Christensen, Janne Winther
core  

Home - About - Disclaimer - Privacy