One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs [PDF]
The aim of the study was to assess the long-term efficacy and safety of Infliximab therapy in the treatment of patients with Behçet’s disease refractory to standard immunosuppressive agents. Twenty-one patients that did not respond to corticosteroids and
CICCIA, Francesco +5 more
core +1 more source
Basophil Activation Test for the In Vitro Diagnosis of Tocilizumab Hypersensitivity
Clinical &Experimental Allergy, EarlyView.
Ana Koren +3 more
wiley +1 more source
Elevated Peripheral CD161+ Treg Cells and Their Clinical Significance in Behçet Syndrome
Objective Behçet syndrome (BS) is a systemic autoimmune vasculitis characterized by immune dysregulation involving multiple immune cell subsets. CD161+ Treg cells exhibit proinflammatory properties and impair immune regulation during inflammation. This study aimed to investigate the alterations in CD161+ Treg cells in BS and their clinical relevance ...
Jiachen Li +9 more
wiley +1 more source
Our golden rule in Behçet's disease: treating the clinical manifestation [PDF]
A Doença de Behçet (DB) é uma vasculite sistémica que pode ser definida na fronteira entre a doença autoimune e autoinflamatória. A sua etiopatogenia ainda não é completamente conhecida, embora saibamos que contribuem factores genéticos (Antigénios de ...
Almeida, I. +4 more
core
Retrospective diagnosis of Behcet’s disease prompted by a false-positive D-dimer [PDF]
Mira Merashli, Paul R. J. Ames
openalex +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Successfully treated isolated renal artery pseudoaneurysm in a patient with Behçet's disease
Renal artery aneurysms and pseudoaneurysms are an uncommon clinical problem with a low incidence rate. They are abnormal dilatations of the vessel lumen with some different natures.
Sihyung Park +5 more
doaj +1 more source
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen +8 more
wiley +1 more source
MEFV Gene Mutations in Behçet’s Disease
Behçet's disease is a chronic inflammatory multisystemic disorder of unknown cause, characterized by orogenital ulcers, uveitis, skin lesions, vascular, locomotor, pulmoner, gastrointestinal, and central nervous system manifestations.
Fazile Hatipoğlu Erdem
doaj
Pathological implications of Th1/Th2 cytokine genetic variants in Beh\ue7et's disease: Data from a pilot study in a Sicilian population [PDF]
Cytokines act as pleiotropic polypeptides able to regulate inflammatory/immune responses and to provide important signals in physiological and pathological processes.
Accardo Palumbo, A. +8 more
core +1 more source

