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Behcet's Disease

Definitions, 2019
Behret (1937) described a chronic, relapsing complex of oral ulceration, genital ulceration, and ocular inflammation. It has been recognized that many other systems may be involved, including the skin, cardiovascular, central nervous, and ...
Hitoshi Asakura   +4 more
semanticscholar   +1 more source

Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Behçet's disease and HLA-B*46:01 for its intestinal involvement.

Digestive and Liver Disease, 2023
BACKGROUND Intestinal involvement in Behçet's disease (BD) is associated with poor prognosis and is more prevalent in East Asian than in Mediterranean populations.
Eun Suk Jung   +15 more
semanticscholar   +1 more source

Behçet's disease: New insights into pathophysiology, clinical features and treatment options.

Autoimmunity Reviews, 2018
Behçet's disease (BD) is a rare systemic vasculitis characterized by oral aphthous ulcers, genital ulcers, ocular lesions and other systemic manifestations.
A. Greco   +7 more
semanticscholar   +1 more source

Critical role of neutrophil extracellular traps (NETs) in patients with Behcet’s disease

Annals of the Rheumatic Diseases, 2019
Objectives Behçet’s disease (BD) is a chronic systemic vasculitis. Thrombosis is a frequent and life-threatening complication. The pathogenesis of BD is poorly understood and evidence supporting a role for primed neutrophils in BD-associated thrombotic ...
Alexandre Le Joncour   +14 more
semanticscholar   +1 more source

Neuro-Behcet's disease: An update on diagnosis, differential diagnoses, and treatment.

Multiple Sclerosis and Related Disorders, 2019
Neuro-Behcet's disease (NBD) is defined as a combination of neurologic symptoms and/or signs in a patient with Behcet's disease (BD). Relevant syndromes include brainstem syndrome, multiple-sclerosis like presentations, movement disorders ...
A. Borhani-Haghighi   +6 more
semanticscholar   +1 more source

Methylation Status of Interleukin-6 Gene Promoter in Patients with Behçet's Disease.

Reumatología Clínica, 2020
BACKGROUND IL-6 mRNA expression is significantly high in many autoimmune diseases such as Behçet's disease; this is often related with more aggressive phenotypes.
Shahriar Alipour   +10 more
semanticscholar   +1 more source

Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management.

Disease-a-month : DM
Behçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract.
Zara Manuelyan, Edward Butt, S. Parupudi
semanticscholar   +1 more source

Assessment of neurocognitive function in patients with Behçet’s disease

Rheumatology
Introduction There is limited knowledge on cognitive performance in Behçet’s disease (BD), the majority of which come from patients with neuro-Behçet’s disease.
R. Ghaleb, Hussin M. Said
semanticscholar   +1 more source

Eye and Behçet's disease.

Journal Francais d'Ophtalmologie, 2019
Behçet's disease is a chronic multisystem disorder characterized by relapsing inflammation for which the underlying histopathology is an occlusive vasculitis. The disease has a high prevalence in the Mediterranean region, Far and Middle Eastern countries.
Imen Khairallah Ksiaa   +7 more
semanticscholar   +1 more source

Surgical Outcomes in Behcet's Disease Patients With Severe Aortic Regurgitation.

Annals of Thoracic Surgery, 2019
BACKGROUND An optimal treatment for aortic regurgitation in Behcet's disease has not been established. We investigated the effect of operative technique, prosthetic material, and immunomodulation therapy on surgical outcomes.
B. Ghang   +9 more
semanticscholar   +1 more source

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