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GLP-1RA Promotes Beige Differentiation in Adipose Tissue
Advances in Clinical Medicineopenaire +1 more source
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Endocrine Regulation of Brown and Beige Adipose Tissue
, 2021Ariana Vargas-Castillo +2 more
semanticscholar +2 more sources
The role of brown and beige adipose tissue in glycaemic control.
Molecular Aspects of Medicine, 2019 For the past decade, brown adipose tissue (BAT) has been extensively studied as a potential therapy for obesity and metabolic diseases due to its thermogenic and glucose-consuming properties. It is now clear that the function of BAT goes beyond heat production, as it also plays an important endocrine role by secreting the so-called batokines to ...
K. Klepac +3 more
semanticscholar +5 more sources
The role of autophagy in brown and beige adipose tissue plasticity
Journal of Physiology and Biochemistry, 2019Since the rediscovery of active brown and beige adipose tissues in humans a decade ago, great efforts have been made to identify the mechanisms underlying the activation and inactivation of these tissues, with the hope of designing potential strategies to fight against obesity and associated metabolic disorders such as type 2 diabetes.
M. Cairó, J. Villarroya
semanticscholar +3 more sources
Aging of Brown and Beige/Brite Adipose Tissue
2018Brown adipose tissue aging and the concomitant loss of thermogenic capacity have been linked to an inability to maintain normal energy homeostasis in late life. Similarly, the ability of white fat to convert into brite/beige adipose tissue declines. This may ultimately exacerbate the progression of age-related metabolic pathologies, such as insulin ...
Antonia, Graja +2 more
openaire +2 more sources
American Journal of Physiology. Endocrinology and Metabolism
Glycogen is a form of energy storage for glucose in different tissues such as liver and skeletal muscle. It remains incompletely understood how glycogen impacts on adipose tissue functionality.
Shixuan Zhuo +8 more
semanticscholar +1 more source
Glycogen is a form of energy storage for glucose in different tissues such as liver and skeletal muscle. It remains incompletely understood how glycogen impacts on adipose tissue functionality.
Shixuan Zhuo +8 more
semanticscholar +1 more source
Brown and Beige Adipose Tissues in Health and Disease
Comprehensive Physiology, 2017ABSTRACTBrown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat develops postnatally and is highly inducible. Beige fat recruitment is mediated by multiple mechanisms, including de novo beige adipogenesis and white‐to‐brown ...
openaire +2 more sources
Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
The FASEB Journal, 2020Abstract Regulatory T cells (Tregs) play essential roles in obesity and diabetes. Here, we report a role of Tregs in enhancing β3‐adrenergic receptor agonist CL316243 (CL)‐stimulated thermogenic program in subcutaneous adipose tissue (SAT), but not in visceral fat.
Wenqian, Fang +5 more
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Transcriptome profile of white, brown and beige adipose tissue
The FASEB Journal, 2022Adipose tissue dysregulation lies at the core metabolic syndrome. White adipose tissue (WAT) has the capacity to store energy, whereas brown adipose tissue (BAT) can dissipate energy through thermogenesis. Newly discovered beige adipocytes are brown like adipocytes recruited in WAT in response to b3‐adrenergic stimulation (CL316 ...
Henry Paz +4 more
openaire +1 more source
The FASEB Journal, 2021
To determine whether ellagic acid (EA) induces the “beige remodeling” of white adipose tissue (WAT), we treated cold‐exposed mice and mouse stromal vascular fraction (SVF) cells with EA, a phytochemical abundant in fruits and vegetables, in particular ...
Woo Yong Park +4 more
semanticscholar +1 more source
To determine whether ellagic acid (EA) induces the “beige remodeling” of white adipose tissue (WAT), we treated cold‐exposed mice and mouse stromal vascular fraction (SVF) cells with EA, a phytochemical abundant in fruits and vegetables, in particular ...
Woo Yong Park +4 more
semanticscholar +1 more source